Samenvatting van het volledige vak farmacologie dus zowel partim I & II (behaald resultaat 19/20)
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Course
Farmacologie
Institution
Universiteit Antwerpen (UA)
Samenvatting van het volledige vak farmacologie dus zowel partim I & II (behaald resultaat 19/20): Dit bevat een uitgebreide samenvatting van Farmacologie gegeven door professor Pieter-Jan Guns & professor Guido De Meyer. De samenvatting bevat al de lessen (deel 1 & 2), informatie uit de cursus en ...
,7 5-Hydroxytryptamine (Serotonine)....................................................................................................35
7.1 Distributie, biosynthese en metabolisme...................................................................................35
7.2 Effecten en functies....................................................................................................................35
7.3 Receptoren.................................................................................................................................36
7.4 Ergotalkaloïden...........................................................................................................................36
8 Purines...............................................................................................................................................38
8.1 ATP & ADP..................................................................................................................................38
8.2 Adenosine...................................................................................................................................38
9 Stikstofoxide......................................................................................................................................39
9.1 Synthese, inactivatie en transport..............................................................................................39
9.2 Effecten.......................................................................................................................................39
9.3 Rol in pathologie.........................................................................................................................39
9.4 Klinische toepassingen................................................................................................................40
10 Lokale hormonen, ontsteking en allergie........................................................................................41
10.1 Histamine..................................................................................................................................41
10.2 Prostaglandinen........................................................................................................................43
10.3 Leukotriënen.............................................................................................................................45
10.4 Bradykinine...............................................................................................................................46
11 Anti-inflammatoire en immunosuppressieve farmaca....................................................................47
11.1 NSAID........................................................................................................................................47
11.2 Glucocorticoïden.......................................................................................................................49
11.3 Antirheumatica (DMARD’s).......................................................................................................52
11.4 Immunosuppressiva..................................................................................................................52
11.5 Anti-jichtmiddelen....................................................................................................................53
12 Hemostase en trombose..................................................................................................................54
12.1 Inleiding....................................................................................................................................54
12.2 Trombocyten............................................................................................................................55
12.3 Antiplaatjesmiddelen................................................................................................................55
12.4 Stollingscascade........................................................................................................................57
12.5 Anti-Stollings GM......................................................................................................................58
12.6 Fibrinolytica..............................................................................................................................60
12.7 Samenvatting GM.....................................................................................................................61
13 Hypolipemiërende farmaca.............................................................................................................63
13.1 Lipoproteïnetransport in het bloed..........................................................................................63
13.2 Atherogenese...........................................................................................................................63
13.3 Hypolipemiërende farmaca......................................................................................................64
14 Hart..................................................................................................................................................67
14.1 Farmaca die hartfunctie beïnvloeden.......................................................................................67
II
, 14.2 Anti-aritmica.............................................................................................................................67
14.3 Inotrope stoffen........................................................................................................................70
14.4 Autonome transmitters en verwante stoffen...........................................................................72
14.5 Anti-anginosa............................................................................................................................72
15 Vasculair systeem............................................................................................................................76
15.1 Contractie en relaxatie van GSC................................................................................................76
15.2 Vasoconstrictoren.....................................................................................................................77
15.3 Vasodilatoren............................................................................................................................78
15.4 Klinische toepassing van vasoactieve GM.................................................................................78
15.5 Nevenwerkingen antihypertensiva...........................................................................................80
16 Diuretica..........................................................................................................................................82
16.1 Functie niertubuli......................................................................................................................82
16.2 Diuretica...................................................................................................................................82
17 Ademhalingsstelsel..........................................................................................................................85
17.1 Regulatie musculatuur, bloedvaten en klieren.........................................................................85
17.2 Farmaca die ademhaling beïnvloeden......................................................................................85
17.3 Bronchiaal astma......................................................................................................................85
18 Maagdarmstelsel.............................................................................................................................88
18.1 Secretie maagzuur, mucus en bicarbonaat...............................................................................88
18.2 Antacida....................................................................................................................................88
18.3 Maagzuursecretie inhibitoren...................................................................................................89
18.4 Behandeling H.pylori................................................................................................................89
18.5 Anti-emetica.............................................................................................................................90
18.6 Laxativa.....................................................................................................................................91
18.7 Antidiarreïca.............................................................................................................................92
18.8 Spasmolytica.............................................................................................................................92
19 Chemische transmissie en werking van GM in CZS..........................................................................93
19.1 Chemische transmissie in CZS...................................................................................................93
19.2 Werking van GM in CZS.............................................................................................................93
19.3 Classificatie psychotrope GM....................................................................................................93
20 AZ als NT..........................................................................................................................................94
20.1 Exciterende AZ..........................................................................................................................94
20.2 Inhiberende AZ.........................................................................................................................94
21 Andere NT en modulatoren in CZS..................................................................................................96
21.1 Noradrenaline...........................................................................................................................96
21.2 Dopamine.................................................................................................................................96
21.3 Serotonine................................................................................................................................97
21.4 ACh...........................................................................................................................................97
III
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