Samenvatting van het volledige vak farmacologie dus zowel partim I & II (behaald resultaat 19/20) aan de hand van flash cards
27 views 1 purchase
Course
Farmacologie
Institution
Universiteit Antwerpen (UA)
Samenvatting van het volledige vak farmacologie dus zowel partim I & II (behaald resultaat 19/20) aan de hand van flash cards: Dit bevat een uitgebreide samenvatting van Farmacologie gegeven door professor Pieter-Jan Guns & professor Guido De Meyer. De samenvatting bevat al de lessen (deel 1 & 2), ...
Charlotte Plessers (s0172911) – 3e BA GEN (2019-2020)
Geneesmiddelen – partim 1
1
,Charlotte Plessers (s0172911) – 3e BA GEN (2019-2020)
2
,Charlotte Plessers (s0172911) – 3e BA GEN (2019-2020)
5-hydroxytryptamine
3
, Charlotte Plessers (s0172911) – 3e BA GEN (2019-2020)
5-hydroxytryptamine = 5-HT = serotonine
Biosynthese & metabolisme:
- Synthese uit L-tryptofaan.
- Afbraak door MAO en aldehyde dehydrogenase tot 5-HIAA.
Classificatie van 5-HT-R (zie H7):
- 7 hoofdtypes (5-HT1-7)
- Type 1 en 2 zijn onderverdeeld in subtypes
Fysiologische effecten:
- GIS: motiliteit, braakreflex
- Bloedplaatjes: opname 5-HT (plasmaconcentratie), vrijgesteld bij aggregatie + zorgt
voor activatie van TRC
- Bloedvaten: VC (via 5-HT1B/1D) of VD (via 5-HT2), rol bij controle van microcirculatie
- Nociceptie: activatie pijngevoelige zenuwen + pijnperceptie in CZS (5-HT3)
- CZS: excitatie (via 5-HT2) of inhibitie (via 5-HT1A), betrokken bij eetlust/stemming/
slaap/hallucinaties/braken/stereotiep gedrag, rol bij depressie
4
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller lemmeslodders. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $8.03. You're not tied to anything after your purchase.