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Lesson 1 Quiz Antiretroviral Medications and Initial Therapy
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Lesson 1 Quiz: Antiretroviral Medications andInitial Therapy
Lesson 1 Quiz: Antiretro viral Medications and Initial Therapy
1
M araviro c is being co nsidered as a part o f t he new antiret ro viral regi men and an HIV
tro pism co recept o r assay is o rdered.
What result is required for maraviroc to be considered appropriate for use?
R5-tropic HI V
Mix ed-tropic H I V
X4-tropic HI V
Dual-tropic HI V
2
Which one of the following medications requires phosphorylation to become
active as an inhibitor of HIV?
Etravirine
Lamiv udine
Atazanavir
Raltegravir
3
According to the Adult and Adolescent ARV Guidelines, at what CD4 threshold
should antiretroviral therapy by recommended for persons with HIV
infection?
W hen the CD4 count d eclines to less than 500 cells/m m 3
W hen the CD4 count d eclines to less than 200 cells/m m 3
W hen the CD4 count declines to less than 350 cells/mm 3
A ntiretroviral therapy is recommended for all, reg ardless of CD4 cell count
4
According to the Adult and Adolescent ARV Guidelines, which one of the
following is classified as a recommended initial regimen for most people with
HIV?
Dorav irine-tenofovir DF-emtricitabine
Efavirenz-tenofovir DF-emtricitabine
Doluteg ravir plus tenofovir alafenamide-emtricitabine
Darunavir plus ritonavir plus tenofovir alafenamide-emtricitabine
5
What is the mechanism of action of the nucleoside transcriptase inhibitors
(NRTIs)?
Induction of a conformation chang e in the rev ers e trans criptas e enzyme
Incorporation into the elong ating primer s trand of HI V DNA with res ultant chain termination
Binding to the R Nas e H reg ion of rev ers e trans criptas e with res ult s eparation of the p66 and
p51 s ubunits
Enzyme inhibition throug h binding of the polymeras e domain binding pock et
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