TEST BANK UNDERSTANDING PHARMACOLOGY: ESSENTIALS FOR MEDICATION SAFETY, 2ND EDITION WORKMAN & LACHARITY
ATI PN PHARMACOLOGY RETAKE 2 VERSIONS 2024 PHARMACOLOGY PN RETAKE PROCTORED COMPLETE EXAM ALL 140 QUESTIONS AND CORRECT DETAILED ANSWERS (VERIFIED ANSWERS) ALREADY GRADED A+
TEST BANK FOR UNDERSTANDING PHARMACOLOGY ESSENTIALS FOR MEDICATION SAFETY 2ND EDITION ALL CHAPTERS
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NR-507 Advanced Pathophysiology
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Advanced Pathophysiology Week 1 Quiz
Question 1
pts
Cells in _____ may act as a reservoir in which HIV can be relatively protected from antiviral drugs.
the lungs
Correct!
Your text here 1
the central nervous system
the thymus gland
bone marrow
HIV may persist in regions where the antiviral drugs are not as effective, such as the
CNS.
Question 2
pts
What is the role of reverse transcriptase in HIV infection?
It transports the RNA into the cell nucleus.
It converts single DNA into double-stranded DNA.
It is needed to produce integrase.
Correct!
It converts RNA into double-stranded DNA.
One particular family of viruses, retroviruses (e.g., HIV) carries an enzyme reverse
transcriptase that creates a double-stranded DNA version of the virus.
Question 3
pts
After sexual transmission of HIV, a person can be infected yet seronegative for _____ months.
Correct!
6 to 14
18 to 20
1 to 2
24 to 36
Antibody appears rather rapidly after infection through blood products, usually within 4
to 7 weeks. After sexual transmission, however, the individual can be infected yet
seronegative for 6 to 14 months or, in at least one case, for years.
,Question 4
pts
What of the following remains a significant cause of morbidity and mortality worldwide?
Starvation
Cardiovascular disease
Correct!
Infectious disease
Traumatic injury
Despite the wide scale implementation of progressive public health and immunization
policies, infectious disease remains a significant cause of morbidity and mortality.
Question 5
pts
Which statement about vaccines is true?
Most bacterial vaccines contain attenuated organisms.
Vaccines provide effective protection for all people against viruses, bacteria, and fungal infections.
Most viral vaccines are made by using dead organisms.
Correct!
Vaccines require booster injections to maintain lifelong protection.
In general, vaccine-induced protection does not persist as long as infection-induced
immunity, thus booster injections may be necessary to maintain protection throughout
life.
Question 6
pts
Which statement is true about fungal infections?
They result in release of endotoxins.
They occur only on skin, hair, and nails.
Correct!
They are controlled by phagocytes and T lymphocytes.
They are prevented by vaccines.
The host defense against fungal infection includes the fungistatic properties of
neutrophils and macrophages. T lymphocytes are crucial in limiting the extent of
infection and producing cytokines to further activate macrophages.
,Question 7
pts
What disease involves the deposition of circulating immune complexes containing an antibody against
host DNA, resulting in tissue damage?
Myasthenia gravis
Pernicious anemia
Correct!
Systemic lupus erythematosus (SLE)
Hemolytic anemia
Deposition of circulating immune complexes containing antibody against DNA produces
tissue damage in individuals with SLE.
Question 8
pts
The class of antibody involved in type I hypersensitivity reactions is
Correct!
IgE.
IgA.
IgG.
IgM.
Type I reactions are mediated by antigen-specific IgE and the products of tissue mast
cells (see Figure 8-1).
Question 9
pts
In which primary immune deficiency is there a partial to complete absence of T-cell immunity?
Bruton disease
Adenosine deaminase (ADA) deficiency
Correct!
DiGeorge syndrome
Reticular dysgenesis
The principal immunologic defect in DiGeorge syndrome is the partial or complete
absence of T-cell immunity.
Question 10
pts
, Deficiencies in which element can produce depression of both B- and T-cell function?
Iron
Magnesium
Correct!
Zinc
Iodine
Deficient zinc intake can profoundly depress T- and B-cell function.
Question 11
pts
During an IgE-mediated hypersensitivity reaction, what causes bronchospasm?
Bronchial edema caused by binding of the cytotropic antibody
Smooth muscle contraction caused by histamine bound to H2 receptors
Bronchial edema caused by chemotactic factor of anaphylaxis
Correct!
Smooth muscle contraction caused by histamine bound to H1 receptors
Acting through the H1 receptors, histamine contracts bronchial smooth muscles, causing
bronchial constriction; increases vascular permeability, causing edema; and causes
vasodilation, increasing blood flow into the affected area (Figures 6-3 and 6-10).
Question 12
pts
A person with type O blood is likely to have high titers of anti-___ antibodies.
A
Correct!
A and B
B
O
Type O individuals, who have neither A or B antigen but have both anti-A and anti-
B antibodies, cannot accept blood from any of the other three types.
Question 13
pts
Hypersensitivity is best defined as a(n)
immunologic reaction of one person to the tissue of another person.
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