Exam (elaborations)
USMLE Step 1 First Aid - Biochemistry 2022 (100% Verified)
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Chromatin structure - Negatively charged DNA loops twice around histone octamer (2 each of the positively charged H2A, H2B, H3, and H4) to form nucleosome bead. H1 ties nucleosomes together in a string. (Think of "beads on a string"; H1 is the only histone that is not in the nucleosome core.) In...
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