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Summary NEOPLASTIC DISEASE AND ITS MANAGEMENT INTRODUCTION. Detailed notes
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Neoplasia: • state of excessive proliferation of cells • No relation to normal growth and tissue repair. • neoplasm or tumor=abnormal tissue mass • rate of proliferation – ranges from slightly above normal to – wild uncontrolled growth – extends and damages adjacent tissues. �...

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Document information

  • October 14, 2022
  • 48
  • 2022/2023
  • Summary

Subjects

  • metaplasia
  • oncogenesis
  • risk fac
  • neoplastic disease and its management introduction
  • neoplasia
  • 2 broad classes • benign tumors • malignant tumors
  • • malignant tumor – commonly known as cancers or cas

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NEOPLASTIC DISEASE AND ITS
MANAGEMENT
INTRODUCTION

LECTURE 1

, Introduction and general principles
• Learning objectives:
By the end of this lecture the learner should be able to;
• Define Neoplastic disease
• Classify and characterize tumours'
• Review factors predisposing to tumours formation
• Review the cell cycle and identify target sites for
anti cancer agents
• Define factors that influence clinical outcome of
cancer treatment

, Definition of Neoplasia
Neoplasia:
• state of excessive proliferation of cells
• No relation to normal growth and tissue repair.
• neoplasm or tumor=abnormal tissue mass
• rate of proliferation
– ranges from slightly above normal to
– wild uncontrolled growth
– extends and damages adjacent tissues.
– rarely exceeds the fastest normal rate of cell
multiplication embryonic development,
intestinal mucosal cells, blood and skin.

, Definition of Neoplasia
Neoplasia excludes abnormally rapidly cell growths
Metaplasia- change from a more specialized cell
to a less specialized cell due to
• prolonged irritation or
• chronic infection eg
• columnal epithelium cell> more resistant
squamous epithelium cells (proliferate very rapidly)
• fibroblasts into osteoblasts giving rise to
new excessive bone growth

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