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Zusammenfassung MBI - EBd T VL3 - Homöotische Gene _ Entwicklung der Gliedmaßenknospen
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MBI - EBd T VL3 - Homöotische Gene _ Entwicklung der Gliedmaßenknospen
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lOMoARcPSD|16349605Vorlesung 3 – Homöotische Gene & Entwicklung der
Gliedmaßenknospen
Begriffserklärung Homöose
- Organe/Segmente nehmen Identität von Organen/Segmenten an, zu denen sie in
serieller Homologie stehen
→ Homöotische Gene bestimmen die Identität von Organen/Segmenten
Homöotische Gene bei Drosophila
Diese 8 Homöotischen Gene liefern den jeweiligen Abschnitten ihre Identität
- Homöotische Gene sitzen in einem Komplex
- Position der homöotischen Gene im Komplex und der
Ort der Wirkung entlang der anterio – posterioren
Körperachse sind kolinear
- Homöotische Gene haben Homöo – Box (Hox) und
kodieren für Transkriptionsregulatoren mit Homöo –
Domäne
- Die einzelnen Gene haben eine hohe Ähnlichkeit
zueinander
- Hox – Gene geben positionelle Information entlang der antero – posterioren Achse
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