psychology-lecture-7-jennifer-stamp

lOMoARcPSD|18482020




Psychology Lecture 3 Unit 3


Intro to Psyo & Nesc I (Dalhousie University)




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, lOMoARcPSD|18482020




Ps
ychologyLect
ure3Uni
t3
Bi
ologi
calBasi
sofMemory

TheBi
ologi
calBasi
sofMemor y
Howarememor i
ess t
ored?
Howcomesmemor iesdon’ti
ncr
eas
ethesi
zeofourbr
ains
?

Memor
yinNeurons
- Hebb’
sLaw ( Donal dHebb)
- Summar i
zedinto2s t
eps( Memor yTrace,Memor yConsolidati
on)
o Neur onst hatfiret ogetherwi r
et ogether
o 1)Whenoneneur onr epeatedl
yfiresandex ci
tesanotherneur onther
eisa
temporarymemor yt r
acethatrev erber
atesacr osst
hes y napseforashort
ti
me
 Memor ytr
acehappenswhenaneur oncommuni catesalotwit
h
anotherneur on
o 2)I ft
hismemor ytraceper si
stsitisfol
lowedbyaper manentchangei nt
he
recei
vi
ngandorex cit
atoryneuron.
 Thi ss t
rengthensthes ynapticconnect i
on
o Pr oposedt hatsomet hi
nghappensbet weencommuni cationthat
str
engthenst he2neur onsr el
ati
onshi p

o Cellassembli
es
 Net worksofcellsthatcommuni cat
ewitheachotherinapart
i
cular
way
 Ther ef
ore,don’tneedt ohavemor ecel
lsj
uststr
engthened
connecti
ons
 Br ai
nchangeswhenwef orm newmemor i
esdoesnotactual
lyget
bi
gger
 Per si
stevenaf t
ers t
imulati
onhasstopped
 Justneeds t
rengthenconnect i
on
o “Useitorloseit
”:i
fthecel lassembli
esarenotsti
mulat
edr epeat
edl
y,
eventual
lythesynapticconnectionsweakenandwef orget

Possibl
eStep1:
- Long-t
er m potent
iati
on(LTP)
o St rengthenedconnect i
onwhenoneneur onrepeat
edlyex ci
t
esanother
o Pyr ami
dal li
cel nhippocampus(lar
ge)cansti
ckanel ectr
odeinitand
recordfrom it
o Sl iceofhippocampusy oucangetint
oneuronalci
rcuit
sbysticki
ng
electr
odesi ncell
o Ex :
 2knownpat hway sI
nput1,I
nput2




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