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6. Aanpassing extra-uteriene leven en problemen eerste levensweken - deel 2 (mulder) ............ 81
6.1. Deel 1: wrap up ....................................................................................................................... 81
6.2. hartafwijkingen ....................................................................................................................... 81
6.2.1. casus: marisse .................................................................................................................. 81
6.2.2. cyanose ............................................................................................................................ 81
6.2.3. hartfalen........................................................................................................................... 86
6.2.4. hartgeruis ......................................................................................................................... 88
6.2.5. Tabel 18. 2 lissauer........................................................................................................... 90
6.2.6. cave ductus afhankelijke aandoeningen .......................................................................... 90
6.3. metabool ................................................................................................................................. 90
6.3.1. temperatuur..................................................................................................................... 90
6.3.2. glucose huishouding ........................................................................................................ 91
6.4. take home messages ............................................................................................................... 93
7. embryologie, ontwikkeling en congenitale afwijkingen van de urogenitale tractus (v hoeck) ... 94
7.1. Embryologie............................................................................................................................. 94
7.1.1. 3 stadia van niervorming .................................................................................................. 94
7.1.2. congenitale afwijkingen van de nieren en de urinewegen ............................................... 96
7.1.3. Besluit .............................................................................................................................. 97
7.1.4. essenties .......................................................................................................................... 97
7.2. Congenitale afwijkingen vd nieren en urinewegen .................................................................. 98
7.2.1. Obstructieve nier ............................................................................................................. 98
7.2.2. Pyeloureterale junctiestenose PUJ................................................................................... 98
7.2.3. VUJ stenose ...................................................................................................................... 99
7.2.4. Posterior urethrakleppen ................................................................................................. 99
7.2.5. Vesicoureterale reflux .................................................................................................... 100
7.2.6. nier met duplex systeem ................................................................................................ 101
7.3. Ontwikkeling vd nierfunctie ................................................................................................... 101
7.3.1. de organisatie van het urogenitaal systeem: korte herhaling ........................................ 102
7.3.2. Renale Bloed Flow voor/na geboorte............................................................................. 102
7.3.3. GFR ontwikkeling ........................................................................................................... 103
7.3.4. Basolaterale Na-K ATPase (motor van de tubulaire functie) .......................................... 104
7.3.5. Ontwikkeling vd proximale tubulus functie .................................................................... 107
7.3.6. de lis van henle .............................................................................................................. 108
7.3.7. Distale tubulus: finetuning van de Na/K homeostase .................................................... 108
7.3.8. De intercalaire cel: Zuur base regeling ........................................................................... 109
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