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Samenvatting Oncologie en palliatieve zorgen - VZC3 - Deel Ilse Demarès $14.11   Add to cart

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Samenvatting Oncologie en palliatieve zorgen - VZC3 - Deel Ilse Demarès

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  • November 29, 2022
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  • 2022/2023
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Oncologie en palliatieve zorg – Ilse Demarès

hoofdstuk 1: Hematologische oncologie..............................................................................5
1 de hematopoëse..............................................................................................................................5
2 Leukemie.........................................................................................................................................6
2.1 Oorzaak.......................................................................................................................................................6
3 Symptomen leukemie......................................................................................................................6
4 Soorten leukemie.............................................................................................................................7
4.1 Acuut...........................................................................................................................................................7
Kenmerken...................................................................................................................................................7
Gevolgen......................................................................................................................................................7
Symptomen..................................................................................................................................................7
4.2 Chronisch....................................................................................................................................................7
Kenmerken...................................................................................................................................................7
5 Acute myeloïde leukemie (AML)......................................................................................................7
4.1 Symptomatologie.......................................................................................................................................7
4.2 Diagnostiek.................................................................................................................................................8
4.3 Behandeling................................................................................................................................................8
Standaardbehandeling.................................................................................................................................8
Behandeling van de oudere patiënt.............................................................................................................8
4.4 Prognose.....................................................................................................................................................8
6 chemotherapie................................................................................................................................8
Bijwerkingen chemotherapie...........................................................................................................................8
Inductiefase......................................................................................................................................................8
Consolidatiefase...............................................................................................................................................9
Tumorlysis syndroom...................................................................................................................................9
Preventie TLS.......................................................................................................................................................... 9
Hematopoëtische stamceltransplantatie (HSCT).............................................................................................9
Transplantperiode......................................................................................................................................10
Mogelijke problemen ten gevolge van stamceltransplantatie..............................................................................11
Mogelijke problemen in de post-transplantperiode..............................................................................................11
autologe HSCT............................................................................................................................................11
Allogene HSCT............................................................................................................................................11

Hoofdstuk 2: het maligne lymfoom...................................................................................12
1 hodgkinlymfoom............................................................................................................................12
1.1 Incidentie..................................................................................................................................................12
Bifasische incidentiecurve..........................................................................................................................12

1

, 1.2 Histopathologie........................................................................................................................................12
1.3 Symptomen..............................................................................................................................................12
1.4 Behandeling..............................................................................................................................................13
Voor stadium I en II met gunstige prognostische factoren....................................................................... 13
Voor stadium III en IV.................................................................................................................................13
1.5 Prognose en late effecten.........................................................................................................................13
Stadium I en II............................................................................................................................................ 13
Stadium III en IV.........................................................................................................................................13
2 Non-hodgkinlymfoom (NHL)..........................................................................................................13
2.1 Symptomen..............................................................................................................................................13
2.2 Stadia........................................................................................................................................................14
2.3 Behandeling..............................................................................................................................................14
Traag-groeiend NHL...................................................................................................................................14
Stadium III en IV bij patiënten > 60j en asymptomatisch......................................................................................14
Stadium III en IV bij jongere patiënten..................................................................................................................14
agressieve lymfomen.................................................................................................................................14

hoofdstuk 3: multipel myeloom........................................................................................15
1 incidentie.......................................................................................................................................15
2 symptomen....................................................................................................................................15
3 Behandeling...................................................................................................................................16
3.1 Jonger dan 65 jaar....................................................................................................................................16
3.2 Ouder dan 65 jaar.....................................................................................................................................16
4 Prognose........................................................................................................................................16
Hoofdstuk 4: hematopoetische stamceltransplantatie (HSCT)...........................................16
1 pre-transplantonderzoeken...........................................................................................................16
2 Conditionering...............................................................................................................................16
2.1 Potentiële complicaties van chemotherapie............................................................................................17
3 ATG................................................................................................................................................17
1 Bijwerkingen................................................................................................................................................17
4 TBI..................................................................................................................................................17
4.1 Verpleegkundige aandachtspunten.........................................................................................................17
5 Toediening van immunosuppressiva.............................................................................................17
5.1 Verpleegkundige aandachtspunten.........................................................................................................18
6 Toediening van de stamcellen.......................................................................................................18
6.1 Mogelijke complicaties op korte termijn.................................................................................................18
1. Risicofactoren op ontwikkelen van VOD................................................................................................18
Verpleegkundige aandachtspunten VOD...................................................................................................18


2

, Behandeling VOD.......................................................................................................................................18
2. Risicofactoren op het ontwikkelen van GVHD.......................................................................................18
Huid............................................................................................................................................................19
Maagdarmstelsel........................................................................................................................................19
Lever...........................................................................................................................................................19
Chronische GVHD (> 3 maand)...................................................................................................................19
Complicaties op langere termijn................................................................................................................19

hoofdstuk 5: andere complicaties van de behandeling van hematologische maligniteiten.19
hoofdstuk 6: Bot- en wekedelenoncologie.........................................................................19
hoofdstuk 7: Neuro-oncologie (hersentumoren)................................................................19
1 oorzaak..........................................................................................................................................19
2 Erfelijkheid.....................................................................................................................................20
3 Hersentumoren bij kinderen..........................................................................................................20
4 Soorten hersentumoren................................................................................................................20
1 Primair.........................................................................................................................................................20
2 Secundair.....................................................................................................................................................20
5 Classificatie....................................................................................................................................20
5.1 Agressiviteit..............................................................................................................................................20
5.2 Lokalisatie.................................................................................................................................................20
5.3 Pathologie.................................................................................................................................................20
6 symptomen....................................................................................................................................20
6.1 Meest voorkomende klachten.................................................................................................................20
Hoofdpijn en misselijkheid.........................................................................................................................21
Wanneer zorgen maken over hoofdpijn?..............................................................................................................21
6.2 Secundaire hydrocefalie...........................................................................................................................21
6.3 Nystagmus................................................................................................................................................21
7 diagnose........................................................................................................................................21
8 behandeling...................................................................................................................................22
8.1 Chirurgie...................................................................................................................................................22
8.2 Radiotherapie...........................................................................................................................................22
8.3 Chemotherapie.........................................................................................................................................22
8.4 Behandeling van intracraniële druk pre-operatief...................................................................................22
Externe ventrikel drainage.........................................................................................................................22
8.5 Radiotherapie met protonen....................................................................................................................22
9 prognose........................................................................................................................................23
10 complicaties van behandeling......................................................................................................23
10.1 Hoge morbiditeit....................................................................................................................................23


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