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Course summary homeostasis and organ systems

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Full course summary of BBS1002 including all cases

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  • December 7, 2022
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Homeostasis and Organ
Systems- BBS1002

Table of contents
Heart (vessels) virtual microscopy + anatomy .................................................................................................. 2

Case 1: Big tension ........................................................................................................................................... 6

Lecture 1- Nutrients of life ............................................................................................................................. 10

Case 2- Get to the heart of the matter ........................................................................................................... 13

Lungs virtual microscopy + anatomy .............................................................................................................. 24

Case 3- “Blood… Quo Vadis?” ......................................................................................................................... 27

Case 4- “Bigger is better?” .............................................................................................................................. 34

Workshop heart ............................................................................................................................................. 40

Case 5- “Live low, train high” ......................................................................................................................... 40

Lecture 3 – Lungs ............................................................................................................................................ 46

Case 6- Cloaca ................................................................................................................................................ 47

Case 7- (Hu)man vs. machine…. ...................................................................................................................... 58

Case 8- Red but not blue ................................................................................................................................ 64

Case 9- Hot and thirsty ................................................................................................................................... 67

Case 10 – the delicate balance between acid and base .................................................................................. 73




1

, Heart (vessels) virtual microscopy + anatomy


Superior
Cranial
Dexter Sinister



Proximal
Posterior or Anterior or
dorsal ventral



Lateral Medial

Caudal Proximal

Distal




Distal

Inferior



Important remarks about directions

➢ Directions are mostly compared to each other: superior vein and inferior vein
➔ Lateral compared to medial -> peripheral to central
➔ Ventral compared to dorsal
➔ Distal compared to Proximal
➔ Anterior compared to posterior
➔ Superficial compared to deep

! Remember in animals walking on 4 legs cranial doesn’t mean the same as in
humans; their head then is referred to as anterior




2

, ➔ Tricuspid valve = right atrioventricular
valve -> atria to ventricle
➔ Bicuspid valve (mitral valve) = left
side -> left atrioventricular valve
➔ Sinus coronarius = drains venous
blood from coronary circulation to the
right atrium of the heart

Signal transduction heart




3

, Circulatory system

➢ Arteries ALWAYS carry blood away from the heart (mostly oxygenated but not
always)
➔ Pulmonary arteries: heart to the lungs
➔ Umbilical arteries: fetus to the maternal placenta
➢ Veins carry blood to the heart (mostly deoxygenated but not always)
➔ Pulmonary veins: lungs to the heart
➔ Umbilical veins: placenta to the fetus

Microvasculature versus macrovasculature

➢ Large vessels versus capillaries, arterioles, and venules

Branches from aorta


1 branchiolic artery
2 common carotid artery
3 subclavian artery (either left or right)




Function circulatory system

- Heat exchange, nutrient delivery, ‘waste pick-up’, brings oxygen, hormone
delivery
➔ Exchange finds place in capillaries (only one cell thick)


Structure of a blood vessel


1. Tunica intima -> one layer of endothelium
on basal lamina, supported by
subendothelial connective tissue; in
arteries the lamina elastica interna
separates layers (visible as wavy line)
2. Tunica media -> layers of smooth muscle
cells separated by ECF (proteoglycans); in
large vessels a lamina elastica interna
separates from next layer
3. Adventitial layer -> connective tissue
(collagenous and elastic fibers), blends in
with connective from organ it is imbedded
in
4. Vas vasorum -> in large vessels vas
vasorum supply vessel wall with blood
➔ Lymph vessels and vasomotor nerves
can be found in the connective tissue



4

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