NURS 663 Exam 1 Questions and
Answers 2022
Bipolar one disorder DSM five criteria - ANSWER-Manic episode: 1+ week of a colon
elevated, expansive or irritable mood and increase energy. 3+ symptoms from B:
distractibility, indiscretion, irresponsible, grandiosity, flight of ideas, activity(Increase
goal-orient), decreased need for sleep, talkativeness or pressured speech.
Bipolar two DSM five criteria - ANSWER-Hypo mania and major depressive disorder:
hypo mania same as mania with decreased severity and duration and no functional
impairment for episode of four or more days and no psychosis
Mixed episodes (bipolar) - ANSWER-Manic and depressive symptoms time by side
usually with comorbid substance abuse increased risk of suicide and psychosis
rapid cycling - ANSWER-Four or more cycles per year no greater than a week well
period
Cyclothymia DSM-V Criteria - ANSWER-Two or more years of mood cycling with
dysthymia and hypo mania decreased intensity than bipolar disorder meets criteria for
hypo mania but does not meet criteria for major depressive disorder
Dysthymia DSM five criteria - ANSWER-HE'S 2 SAD depressive symptoms lasting two
or more years that is subsydromal characterized by hopelessness decreased energy,
decrease self-esteem for two years, abnormal sleep, abnormal appetite impaired
decision-making.
MAOÍ Mechanism of action generally - ANSWER-Catalyzes the deamination of
monoamines intracellularly and MAO transport Reuptake extracellular monoamines
MAO-A Mechanism of action - ANSWER-MAO-A Oxidizes serotonin norepinephrine
and epinephrine
MAO-B Mechanism of action - ANSWER-Oxidizes phenylalanine
MAO-A and MAO-B mechanism of action - ANSWER-Oxidizes dopamine non-
preferentially
MAOs Neumonic -2 - ANSWER-Date with Tyra banks with wine and cheese in Maui—
can cause hypertensive crisis related to tyramine from aged food.
MAWIs= my arms weight increased= effective for atypical depression
, MAOs adverse effects-6 - ANSWER-Hypertensive crisis, diet restriction, avoid meds,
five week after Prozac, two week after other antidepressants, no other medications for
two weeks after discontinuing
MAOs diet restriction-4 compounds - ANSWER-Tyrosine, high tyramine, tryptophan,
phenylalanine
Tyrosine foods-10 - ANSWER-Aged cheese, aged wine, fava or broad bean pods,
sauerkraut, soy sauce, tap or draft beer, overripe fruit, cured meat, spoiled food
MAOs drugs to avoid- 6 - ANSWER-Antidepressants, Dextromethorphan, stimulants,
sympathomimetics, meperidine, disulfiram
MAOs side effects 11 - ANSWER-Increased weight, drowsy, dizzy, orthostatic
hypotension, tremor, headache, dry mouth, constipation, change in sexual drive,
peripheral Edema, sweating
Tricyclic mechanism of action - ANSWER-Inhibit 5HT2, norepinephrine, dopamine and
reuptake slows. Amino group interferes with ASP - 98 in HSERT. Causing down
regulation of receptors.
Tricyclic side effects - ANSWER-Anticholinergic effects (dry mouth, blurred vision,
constipation, urine retention, impotence). Histamine effects (sedation, increased
weight). Adrenergic alpha receptor (postural hypotension). Direct membrane effects
(decrease seizure threshold and arrhythmias). 5HT2 receptor (increase weight and
decrease anxiety).
Amitriptyline dosing/Class - ANSWER-Start at 25 to 50 mg per day, titrate 25 to 50 mg
per day per week, Max dose is 300 mg per day/TCA
Names of tricyclics 10 - ANSWER-Amitriptyline, nortriptyline, clomipramine, imipramine,
protriptyline, doxepin, amoxapine, desipramine, mapratiline, tripramine
Tricyclics are useful-2 - ANSWER-Pain, migraine
Tricyclics adverse effects-2 - ANSWER-Overdoses are cardiotoxic, high potency
increases the risk of mania
Nortriptyline mnemonic - ANSWER-No-triptyline equals less sedation and hypotension
Tricyclics mnemonic-2 - ANSWER-Think car goes over tricycle to remember that an
overdose is cardiotoxic. Do you remember mechanism think trans =serotonin and
norepinephrine Chans= Na+ and Ca+ Ans= ACH and histamine
