ACAAI Review CHAPTER 5| 73 QUESTIONS| WITH COMPLETE SOLUTIONS

Early-phase mechanisms are allergen-induced mast cell secretion of histamine, prostaglandins, and leukotrienes; late-phase mechanisms are eosinophil chemotaxis, caused by chemical mediators produced in the early reaction correct answer: What are the primary mechanisms of early- and late-phase allergic rhinitis? They block both the early-phase (rhinorrhea, sneezing) and late-phase (congestion) responses correct answer: Intranasal corticosteroids block which phase(s) of the allergic response? Preexisting allergic rhinitis; about one-third of women with AR experience symptom exacerbation during pregnancy correct answer: What is the most common cause of rhinitis during pregnancy? Turbinate edema resulting from the release of thyroid-stimulating hormone correct answer: Why can nasal congestion or rhinorrhea develop in hypothyroidism? Check β2-transferrin in nasal secretions for suspected CSF rhinorrhea correct answer: Acute onset of unilateral, clear rhinorrhea that is worse when the patient leans forward should prompt evaluation with what test? Fluid extravasation leads to mucosal edema and venous constriction correct answer: What is the pathophysiologic mechanism for pale, boggy nasal mucosa in patients with AR? Expansile growth of fungal hyphae and generation of allergic mucin correct answer: How does AFRS lead to bone destruction and extension outside the sinuses? Increases of IgE 10% in a patient's postsurgical IgE correlate with increased risk of recurrence correct answer: What lab values can be monitored to assess interval progression of AFRS s/p FESS? No, studies have found poor correlation correct answer: Does serum-specific IgE to fungal element correspond to species of fungus found in allergic mucin of patients with AFRS? Total serum IgE level is not one of the Bent and Kuhn diagnostic criteria for AFRS correct answer: What value of total serum IgE is necessary to diagnose AFRS? Identification of fungal sensitization and preparation for post-FESS allergen immunotherapy to fungal and nonfungal allergens correct answer: In a patient with recurrent sinusitis and CT findings of pansinusitis and inspissated mucin, what role(s) does skin-prick testing to aeroallergens play?