clinical reasoning and research in internal medicine
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Vrije Universiteit Amsterdam (VU)
Geneeskunde
Minor: Internal Medicine
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Colleges Transgender Care
Inhoud
Introduction 28/11 ................................................................................................................................2
Etiology 28/11 .......................................................................................................................................2
Diagnose 28/11 ......................................................................................................................................3
Gender dysphoria in children and adolescents 29/11 ...........................................................................4
Long-term outcomes in gender diverse adolescents 29/11 ...................................................................5
NBGQ 2/12 ............................................................................................................................................6
Biology of sex differences and disorders of sexual development 5/12 ..................................................7
Endocrine treatment of transgender adults 5/12 ..................................................................................7
Adolescenten 6/12 ................................................................................................................................8
Cancer risk and mortality 6/12 ............................................................................................................10
Seks steroids and bone 6/12 ................................................................................................................10
Hormones and sleep 9/12 ...................................................................................................................11
Cardiovascular risk 9/12 ......................................................................................................................11
Fertility 12/12 ......................................................................................................................................11
Surgery in transmasculine persons 12/12 ............................................................................................12
Gender affirming surgery transmen 13/12 ..........................................................................................13
Mastectomy and gender affirming surgery in transmen 13/12 ...........................................................13
Sexual wellbeing in transgender people 19/12 ....................................................................................15
Feminizing facial surgery 19/12 ...........................................................................................................15
, Introduction 28/11
Sex: chromosomes
Gender: psychosocial
Cisgender: alignment seks and gender
Transgender: incongruence
Language: non pathologising or stigmatising, avoid employing misgendering language, birth seks not
biological male/ female. Transgender is an adjective not a noun
Etiology 28/11
Etiology: the cause, set of causes, or manner of causation of a disease or condition
Relevance
To prove that it is actually something
Recognition
Acces to healthcare
Insurance
Public policy
Acceptance of family
More knowledge
Potential harms
Patholizing
Stigmatizing
Discrimination
Risk of oversimplification
Looking for "cure"
John Money: gender neutrality at birth theory, penis weggehaald en als vrouw opgevoed. Uiteindelijk
suicide gepleegd.
Milton Diamond: sexuality at birth theory. Prenatal genetic and hormonal influences -> male or femal
sexual identity. Leads to bias in interaction with environment.
Twin studies: 30-60% variance explained by genetic
Regional sex differences in volume and tissue density: amygdala, hippocampus, insula
-> implicated in seks- biased neuropsychiatric conditions (autism, depression)
Veel overlap tussen mannen en vrouwenbreinen. Meestal mosaïk van male and female areas.
TG people seem to present with own phenotype unique brain, rather than female or male spectrum
Similarities with experienced gender
-body perception hypothesis?
Samenvatting
Verschilllen man vrouw
En verschillen per persoon
Key messages
Biopsychosocial perspective
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