VAN OFFEL 70
7.1. CALCIUM 70
7.1.1. ALGEMEEN 70
7.1.2. FUNCTIES VAN CA 70
7.1.3. CALCIUM HOMEOSTASE 70
7.1.4. ESSENTIE VAN VITAMINE D 71
7.2. FUNCTIE EN STRUCTUUR VAN HET BOT 72
7.2.1. STRUCTUUR: 72
7.2.2. FUNCTIES: 72
7.3. BOT TURNOVER 75
7.3.1. DOEL BOT TURNOVER 75
7.3.2. FUNCTIONELE UNITS: OSTEOBLAST EN OSTEOCLAST 75
7.3.3. PROCES VAN BOTTURNOVER 76
7.3.4. BESLUIT 76
7.4. APATIET 76
7.5. BOTFORMATIE 76
7.6. BOTRESORPTIE 77
78
7.7. OSTEOPOROSE 78
7.7.1. DEFINITIE 78
7.7.2. PATHOGENESE 78
8. KLINIEK VAN OSTEOPOROSE 79
8.1. LOW IMPACT FRACTUREN 79
8.1.1. INDEUKINGSFRACTUREN BIJ VROUWEN LEIDEN TOT 79
8.2. RISICOFACTOREN 79
8.3. DIAGNOSE: 80
8.3.1. WHO-DEFINITIE VAN OSTEOPOROSE 81
8.4. DIFFERENTIAALDIAGNOSE: VERLIES VAN BOTMASSA 82
8.4.1. OSTEOPOROSE 82
8.4.2. OSTEOMALACIA 82
8.4.3. HYPERPARATHYROÏDIE 83
8.4.4. MALIGNITEITEN 83
8.4.5. LABO: ONDERSCHEID MAKEN 83
8.5. THERAPIE: 84
4
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