Samenvatting Pathofysiologie I, HO 1 (J000483A, UGent, 2022)
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Course
Pathofysiologie I (J000483A)
Institution
Universiteit Gent (UGent)
Samenvatting van de cursus pathofysiologie I hoofdstuk 1 + de slides. Al de afbeeldingen/schema's van op de ppt-slides zijn in de samenvatting geïntegreerd. Ook notities uit de les zijn erin verwerkt.
Ø kleine
moleculen
volgens
c-‐/elektrische
gradiënt
o gefaciliteerde
diffusie
mbv
transporteiwit
(carrier)
§ bv.
glucose
van
ISV
nr
ICV
o openen
ionenkanalen
oiv
§ binding
ligand
op
receptor
=
ligand-‐gated
kanalen
§ wijziging
in
Em
=
voltage-‐gated
=
spanningsgevoelige
kanalen
Ø kleine
moleculen
tegen
c-‐/elektrische
gradiënt
in
o actief
transport:
§ energie
nodig
• energie
halen
uit
afbraak
ATP
§ transport
via
transporteiwitten
=
ATP-‐asen
enzymen
=
ATP-‐pompen
• Na+/K+-‐ATP-‐ase
=
membraanpotentiaal
• H+/K+-‐ATP-‐ase
=
maagmucosa
• Ca2+-‐ATP-‐ase
=
spiercellen
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