Samenvatting Pathofysiologie I, HO2 (J000483A, UGent, 2022)
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Course
Pathofysiologie I (J000483A)
Institution
Universiteit Gent (UGent)
Samenvatting van de cursus pathofysiologie I hoofdstuk 2 + de slides. Al de afbeeldingen/schema's van op de ppt-slides zijn in de samenvatting geïntegreerd. Ook notities uit de les zijn erin verwerkt.
o minder
ATP
gevormd
in
cel
à
ATP-‐aangedreven
transportmech.
verzwakken
Ø hersenen
gevoelig
voor
hypoxische
beschadiging
o na
4-‐6
min
hypoxie
à
afsterven
hersenweefsel
Ø verlies
ionenbalans
in
hypoxische
cellen
o gevolg:
Ca-‐accumulatie
IC
à
activatie
Ca-‐afh.
proteasen
à
afbraak
cellulaire
componenten
o bv.
neurodegeneratie
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