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Samenvatting Neuromusculaire aandoeningen
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Cursus neuromuscular diseases vertaald in het Nederlands
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Neurokinesitherapie 2:Titularis: Prof. Dr. Wim Saeys
Docente: Quirine Schatteman
3e Bachelor Revalidatiewetenschappen en Kinesitherapie
Faculteit Geneeskunde en Gezondheidswetenschappen
Universiteit Antwerpen
, NEUROMUSCULAIRE/NEURODEGENERATIEVE/PERIFERE NEUROLOGISCHE
AANDOENINGEN
Academiejaar 2022-2023
INHOUD: Neuromusculaire ziekten
A. Amyotrofische laterale sclerose [5-10].........................................................................5
1. Algemene inleiding................................................................................................................5
2. Incidentie en etiologie...........................................................................................................6
3. Diagnose en klinische presentatie..........................................................................................7
a. Motorische tekorten...............................................................................................................7
b. Cognitieve en gedragsveranderingen.....................................................................................8
c. Symptomen en tekenen..........................................................................................................8
4. Beheer van ALS......................................................................................................................9
a. Spasticiteit..............................................................................................................................9
b. Pijn..........................................................................................................................................9
c. Spierkrampen.......................................................................................................................10
d. Dysfagie en dysartrie............................................................................................................10
e. Respiratoire insufficiëntie.....................................................................................................11
f. Depressie..............................................................................................................................11
g. Vallen....................................................................................................................................11
h. Oefentherapie [11]...............................................................................................................11
i. Over het algemeen...............................................................................................................12
5. Conclusie [5, 6].....................................................................................................................14
B. De ziekte van Charcot-Marie-Tooth en aanverwante neuropathieën [12-14]..............15
1. Zaak.....................................................................................................................................15
2. Inleiding...............................................................................................................................15
a. Oorzaak, diagnostiek en classificatie [16].............................................................................15
b. Genetica van CMT.................................................................................................................16
3. Klinische presentatie............................................................................................................16
a. Patronen van klinische presentatie......................................................................................16
2
, NEUROMUSCULAIRE/NEURODEGENERATIEVE/PERIFERE NEUROLOGISCHE
AANDOENINGEN
Academiejaar 2022-2023
b. Natuurlijke historie...............................................................................................................17
4. Behandeling: multidisciplinaire aanpak...............................................................................18
a. Beheer van comorbiditeiten en complicaties.......................................................................18
b. Therapeutica.........................................................................................................................20
c. Revalidatie............................................................................................................................21
d. Chirurgische ingrepen...........................................................................................................23
5. Conclusie: de noodzaak van multidisciplinaire zorg.............................................................23
C. Guillain-Barré syndroom [15-18]................................................................................25
1. Inleiding...............................................................................................................................25
a. Achtergrondinformatie.........................................................................................................25
b. Pathofysiologie.....................................................................................................................25
2. Diagnostiek..........................................................................................................................26
a. Diagnostische tests...............................................................................................................27
3. Beheer van het Guillain-Barré-syndroom.............................................................................27
a. Immunotherapie...................................................................................................................28
b. Fysiotherapie........................................................................................................................28
4. Fysiotherapie.......................................................................................................................28
a. Geschiedenis.............................................................................................................................28
b. Klinisch/fysisch onderzoek........................................................................................................29
c. Behandeling..............................................................................................................................29
5. Prognose..............................................................................................................................30
6. Conclusie..............................................................................................................................31
D. Kritieke ziekte polyneuropathie [19-27].....................................................................31
1. Inleiding..................................................................................................................................31
a. Incidentie en etiologie [20,21]..............................................................................................31
b. Pathofysiologie [22]..............................................................................................................31
2. Diagnostiek [22,23].................................................................................................................32
3
, NEUROMUSCULAIRE/NEURODEGENERATIEVE/PERIFERE NEUROLOGISCHE
AANDOENINGEN
Academiejaar 2022-2023
3. Beheer [24,27].........................................................................................................................32
4. Fysiotherapie...........................................................................................................................33
a. Criteria voor beginnende fysiotherapie....................................................................................33
b. Meetbenaderingen...................................................................................................................33
c. Fysieke interventiestrategieën..................................................................................................34
d. Behandeling..............................................................................................................................34
7. Prognose [24,27,28].............................................................................................................35
8. Conclusie[24].......................................................................................................................35
E. Door lachgas veroorzaakte demyelinisatie (NOID) [31-34]..........................................36
1. Inleiding..................................................................................................................................36
a. Pathofysiologie [31]..............................................................................................................36
b. Klinische vertegenwoordiging...............................................................................................36
2. Diagnostiek [32]......................................................................................................................37
a. Diagnostische tests...................................................................................................................37
9. Beheer [33]..........................................................................................................................37
10. Fysiotherapie.......................................................................................................................38
11. Prognose..............................................................................................................................38
12. Conclusie.............................................................................................................................38
F. Referenties.................................................................................................................39
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