Other
Chapter 3 practice questions metabolism and toxicology
- Course
- Institution
- Book
This document provides the practice questions from the topics of chapter 3.
[Show more]
Connected book
Book Title:
Author(s):
- Edition:
- ISBN:
- Edition:
More summaries for
-
Chapter 18 practice questions metabolism and toxicology.
-
Chapter 18 extra questions metabolism and toxicology.
-
Chapter 6 practice questions metabolism and toxicology.
Seller
Follow
tymozwakenberg
Reviews received
Content preview
1. The severity of a toxicant depends, in large part, on the concentration of thetoxicant at its site of action. Which of the following will decrease the amount of
toxicant reaching its site of action?
- excretion via the kidneys.
2. Toxication (or metabolic activation) is the biotransformation of a toxicant to a
more toxic and reactive species. Which of the following is not a reactive
chemical species commonly formed by toxication?
- hydrophilic organic acids.
3. Which of the following is not an important step in detoxication of chemicals?
- formation of redox-active reactants.
4. Regarding the interaction of the ultimate toxicant with its target molecule,
which of the following is false?
- The noncovalent binding of a toxicant to an ion channel irreversibly inhibits
ion flux through the channel.
5. All of the following are common effects of toxicants on target molecules
EXCEPT:
- opening of ion channels.
6. Which of the following proteins functions to prevent the progression of the cell
cycle?
- IκB.
7. Which of the following would have the largest negative impact on intracellular
ATP levels?
- interference with electron delivery to the electron transport chain.
8. What happens when a toxicant induces elevation of cytoplasmic calcium
levels?
- Mitochondrial uptake of calcium dissipates the electrochemical gradient
needed to synthesize ATP.
9. Cytochrome c is an important molecule in initiating apoptosis in cells. All of
the following regarding cytochrome c are true EXCEPT:
- Caspases are proteases that increase cytoplasmic levels of cytochrome c.
10. All of the following regarding DNA repair are true EXCEPT:
- In nucleotide excision repair, only the adduct is cleaved, and the gap is then
filled by DNA polymerase.
11. Apoptosis can serve as a tissue repair process in a number of cell types. In
which of the following cell types would this be a plausible mechanism of tissue
repair?
- gastrointestinal epithelium.
12. Which of the following is NOT associated with carcinogenesis?
- normal p53 function.
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller tymozwakenberg. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $5.96. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
77988 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now