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Chapter 13 practice questions metabolism and toxicology.
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1. The impairment of hepatic function can have numerous negativeconsequences. Which of the following is likely NOT caused by impaired
hepatic function?
- hyperglycemia.
2. All of the following statements regarding the liver are true EXCEPT:
- The liver manufactures and stores bile.
3. Activation of which of the following cell types can result in increased secretion
of collagen scar tissue, leading to cirrhosis?
- Ito cell.
4. Wilson’s disease is a rare genetic disorder characterized by the failure to
export which of the following metals into bile?
- copper.
5. Which of the following is NOT characteristic of apoptosis?
- cell swelling.
6. A patient suffering from canalicular cholestasis would NOT be expected to
exhibit which of the following?
- increased bile formation.
7. Which of the following statements regarding liver injury is FALSE?
- Hydrophilic drugs readily diffuse into hepatocytes because of the large
sinusoidal fenestrations.
8. The inheritance of a “slow” aldehyde dehydrogenase enzyme would result in
which of the following after the ingestion of ethanol?
- nausea.
9. Which of the following is NOT a common mechanism of hepatocellular injury?
- increased transcytosis between hepatocytes.
10. Ethanol is not known to cause which of the following types of hepatobiliary
injury?
- canalicular cholestasis.
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