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Samenvatting virologie (alle hoofdstukken + afbeeldingen)
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samenvatting virologie hoofdstuk slides + notities
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Samenvatting virologie1 Hoofdstuk 1. Inleiding
1.1 Situering van virussen
Buiten 5 rijken volgens Whittacker
1.2 Algemene eigenschappen van virussen
1.3 Vermenigvuldiging van virussen
Intracellulair:
1) Initiële stap adsorptie en penetratie
2) Eclipse fase virus niet opspoorbaar; replicatie genoom/eiwitcapside
3) Maturatie assemblage alle deeltjes
4) Vrijkomen nieuwe deeltjes vrij
1.4 Heterogene groep van virussen
Eenvoudige/naakte virussen:
- Tabaksmozaïekvirus (TMV): staafvormige holle buis; RNA
- Adenovirus: icosaëder; DNA
Virussen met enveloppe:
Enveloppe:
Membraan uit eiwitten, koolhydraten en lipiden
Soms uit heamagglutinines en/of enzymes
Afkomstig van delen gastheercel
- Influenza virus
, Complexe virussen:
- (bacterio)fagen: capside ingewikkelder van bouw kop/staart morfologie
o Kop: te vergelijken met capside sferische virussen; bevat genoom
o Staart: holle buis waardoor genoom passeert bij infectie cel
o Pootjes: op uiteinde staart; draden voor vasthechting aan gastheercel
- Pokkenvirus (Vaccinia):
o DNA: centraal gelegen biconcave schijf omring door verschillende
membranen uit eiwitten en lipiden
2 Indeling van virussen
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