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Samenvatting LDM2DAVN tentamen Genetica en voortplanting

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Tentamenstof voor het tentamen Genetica en Voortplanting van de module LDM2DAVN (Integraal werken aan de optimale houderij) van de studie Diermanagement aan Hogeschool van Hall Larenstein: Uit het boek ‘Biology’ van Campbell, hoofdstukken 13, 14, 15, 16, 19, 20, 21, 22, 23. Hoofdstuk 45 en 46 ...

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Tentamenstof voor het tentamen Genetica en Voortplanting van de module LDM2DAVN (Integraal
werken aan de optimale houderij) van de studie Diermanagement aan Hogeschool van Hall
Larenstein:

Uit het boek ‘Biology’ van Campbell, hoofdstukken 13, 14, 15, 16, 19, 20, 21, 22, 23. Hoofdstuk 45
en 46 aan de hand van de hoorcolleges ‘Voortplanting en hormonen’, ‘Embryologie’ en ‘Geboorte
en ontwikkeling’.

Hoorcollege ‘Genetica: Inteelt en verwantschap’

Module ‘Duurzame fokkerij’ hoofdstuk 1, 2 en 4



Chapter 13: Sexual life cycles and meiosis
 Chromosome: carries genetic information in the form of genes
 Genome: the haploid set of chromosomes in a gamete pr micro-organism, or in each cell of a
multicellular organism. Complete set of genes.
 Locus: the position of a gene or mutation on a chromosome
 DNA: main constituent of chromosomes. The carrier of genetic information.
 Mutation: a change in the nucleotide sequence of an organism’s DNA or in the RNA of a virus
 Allele: any of the alternative versions of a gene that may produce distinguishable phenotypic
effects
 Sex chromosomes: X and Y
 Autosomes: all other chromosomes
 Diploid cell: any cell with two chromosome sets, only diploid cells can undergo meiosis.
 Meiosis: a form of cell division in which each daughter cell receives half the amount of DNA
as the parent cell. Meiosis consists of two phases, meiosis I (prophase I, metaphase I,
anaphase I, telophase I) and meiosis II. This results in 4 daughter cells with different sets of
chromosomes.
 Mitosis: a form of cell division in which a parent cell duplicates all its contents (including
chromosomes) and splits to form two identical daughter cells.
 Chiasma: site of crossing over
 Independent assortment of chromosomes: amount of possible combinations when
chromosomes assort independently= 2^n , in which n is the haploid number.
 Crossing over: occurs when two chromosomes move closer together, results in synapsis
(fusion). When the chromatids break, genetic information is exchanged and two recombinant
chromosomes are made.
 Random fertilization: any sperm can fuse with any ovum (unfertilized egg)




Chapter 14: Mendel

,  Mendel’s hypothesis: parents pass on discrete heritable units (genes)
 Character: heritable feature that varies among individuals
 Trait: variant for a character
 Hybridization: crossing of two true-breeding individuals
 P-generation: parent generation, true-breeding parents
 F1-generation: first filial generation, the hybrid offspring
 F2-generation: result of allowing hybrids to self-pollinate or cross-pollinate with other
hybrids
 Dominant allele: allele that is fully expressed in the phenotype of a heterozygote
 Recessive allele: allele whose phenotypic effect is not observed in a heterozygote
 Homozygote: has a pair of identical alleles for a gene encoding a character
 Heterozygote: has two different alleles for a gene encoding a character
 Phenotype: visible appearance/traits
 Genotype: genetic makeup
 1st concept of Mendel’s model: alternative versions of genes (alleles)
 2nd concept of Mendel’s model: Organism inherits two alleles, one from each parent
 3rd concept of Mendel’s model: dominance (dominant and recessive allel)
 4th concept of Mendel’s model: law of segregation
 Law of segregation: the two alleles for a heritable character segregate during gamete
formation and end up in different gametes.
 Testcross: breeding an organism with an unknown genotype with a recessive homozygote to
reveal the genotype
 Dihybrid: individual that is heterozygote for two characters (YYRR x yyrr YyRr)
 Dihybrid cross: a cross between F1 dihybrids
 Complete dominance: phenotypes of the heterozygote and dominant homozygote are
indistinguishable
 Incomplete dominance: neither allele is completely dominant and the F1-hybrid has a
phenotype somewhere between the two alleles
 Pleiotropy: gene affects multiple traits
 Polygenic inheritance: more than one gene affects a trait
 Quantative characters: many characters are not one or two discrete characters, but vary in
the population
 Genetic diseases: many genetic disorders are inherited in a recessive way and only show up
in homozygote recessive individuals. Carriers of a genetic disease (heterozygote) are
phenotypically not effected




Chapters 15+16: Inheritance
 Morgan’s experiments

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