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Samenvatting Overzicht Algemene Heelkunde Inflammatie en Wondheling
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🩹Inflammatie en Wondheling
Algemene principes van inflammatie
definitie
inflammatie =
reactie op schadelijke prikkel, nodig voor heling
schadelijke prikkel → arachidonzuur → inflammatoire mediatoren
doel = prikkel elimineren en heling starten
lokale inflammatoire reactie
vasculaire respons
vasodilatatie
⬆ permeabiliteit
uittreden fibrinogeen → fibrine
uittreden vocht
oedeem → zwelling, druk, pijn
⬆ stollingsneiging→ microthrombi
cellulaire respons
aantrekken polymorphonucleairen
neovascularisatie
koorts
symptomen
rubor
tumor
calor
Inflammatie en Wondheling 1
, dolor
functio laesa
algemene behandelingsprincipes (3)
etiologisch
chirurgisch
drainage abces
verwijderen vreemd voorwerp
anti-infectieus
antibacterieel
antiparasitair
antiviraal
systemisch anti-inflammatoir
NSAID’s
corticosteroiden (niet bij bact infectie)
antihistaminica
lokaal anti-inflammatoir
afkoelen/cryotherapie (icepacks, koud water, ...)
drukverband ( ⬇oedeem en pijn)
lokale/regionale anesthesie
traumatische letsels
principes onderzoek
ABCD
first life, then limb
volgorde onderzoek
patient bewust?
hapt naar adem?
ademweg vrij, verplaatsing lucht van en naar longen?
Inflammatie en Wondheling 2
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