In diesem Skript werden die Inhalte der Vorlesung "Grundlagen der Arzneiformenlehre" (zweites Fachsemester, Düsseldorf) sowie die Seminare zu dem begleitenden Praktikum "Arzneiformenlehre" (drittes Fachsemester, Düsseldorf) ausführlich behandelt. Beginnend mit der Gesetzeslage (Arzneimittelsgese...
, Verwendete Zusatzsstoffe .......................................................................................................................................................49
Herstellung ...................................................................................................................................................................................49
Cremes (nach DAC-NRF I.6.3.2) ..............................................................................................................................................49
Gele (nach DAC-NRF I.6.3.2) ...................................................................................................................................................49
Salben (nach DAC-NRF I.6.3.2) ...............................................................................................................................................50
Pasten .......................................................................................................................................................................................50
Geräte und Techniken .............................................................................................................................................................50
Qualitätskontrolle .........................................................................................................................................................................50
Beurteilung der Phasenlage ....................................................................................................................................................51
Grenzpartikelbestimmung mittels Grindometer .....................................................................................................................51
Spreitbarkeit mittels Extensometer ........................................................................................................................................51
Biopharmazie ...............................................................................................................................................................................51
Suppositorien ...................................................................................................................................................................................52
Darreichungsformen ....................................................................................................................................................................52
Eigenschaften von Suppositorien ...............................................................................................................................................52
Grundstoffe ..............................................................................................................................................................................52
Hilffstoffe ..................................................................................................................................................................................52
Herstellung (DAC I.12.3) ..............................................................................................................................................................52
Verdrängungsfaktor .................................................................................................................................................................53
Münzel-Methode ......................................................................................................................................................................53
Weitere Herstellungstechniken ...............................................................................................................................................54
Qualitätskontrolle .........................................................................................................................................................................54
Vaginalzäpfchen ...............................................................................................................................................................................55
Darreichungsformen ....................................................................................................................................................................55
Monographien: Vaginalzäpfchen (Ph. Eur.) ............................................................................................................................55
Eigenschaften von Vaginalzäpfchen ...........................................................................................................................................55
Grundmassen ...........................................................................................................................................................................55
Herstellung ...................................................................................................................................................................................56
Qualitätskontrolle .........................................................................................................................................................................56
Biopharmazie ...............................................................................................................................................................................56
Augentropfen ....................................................................................................................................................................................57
Darreichungsformen ....................................................................................................................................................................57
Monographien: Zubereitungen zur Anwendung am Auge (Ph. Eur.) .....................................................................................57
Monographien: Augentropfen (Ph. Eur.) .................................................................................................................................58
Monographien: Augenbäder (Ph. Eur.) ....................................................................................................................................58
Monographien: Pulver zur Herstellung von Augentropfen und Pulver zur Herstellung von Augenbädern .........................59
Monographien: Halbfeste Zubereitung zur Anwendung am Auge .........................................................................................60
Monographien: Augeninserte ..................................................................................................................................................60
Grundlagen ...................................................................................................................................................................................61
Eigenschaften von Augentropfen ................................................................................................................................................61
Hilfsstoffe .................................................................................................................................................................................61
Besonderheiten der Herstellung von Zuebreitungen zur Anwendung am Auge ......................................................................61
Methoden zur Herstellung steriler Zubereitungen (nach Ph. Eur.) .......................................................................................61
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