Class notes
Vías de administración
- Course
- Institution
tipos de administración de los medicamentos: parenteral, enteral
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ENTERALES VÍA SUBCUTÁNEAMás simple Absorción > Vía IM
+ empleada ≠Fenómeno del 1°paso
Segura
Económica
Aprovechan las barreras de defensa del organismo
VÍA ORAL
VÍA INTRAMUSCULAR
Absorción: duodeno
Fenómeno del 1°paso Absorción: depende del músculo
Versátil ≠Fenómeno del 1°paso
Soluciones acuosas Soluciones acuosas: liberación y absorción rápida
Presencia de alimentos, pH gástrico bajo, enzimas Soluciones oleosas: liberación lenta
digestivas pueden afectar la absorción
• Glúteo mayor
VÍA SUBLINGUAL
• Deltoides
Efecto rápido e intenso • Vasto externo
≠Fenómeno del 1°paso
Tx de urgencia y emergencia
Ruta: Vena SL, VYI, VCS, corazón VÍA INTRADÉRMICA
VÍA RECTAL Volúmenes pequeños
Para pruebas de hipersensibilidad
Absorción: errática o incompleta No posee utilidad terapéutica
Evita parcialmente el fenómeno del 1°paso
- empleada
PARENTERALES (INYECTABLES)
No tienen límite de volumen
Emplean fármacos en solución
VÍA INTRAVENOSA OTRAS VÍAS
Biodisponibilidad: 100% Inhalatoria
+ rápida Intranasal
99% fármacos deben ser diluidos Tópica
La vía se cambia c/48h Transdérmica
Vena cefálica, basílica, cubital media, NOTA
metacarpianas-dorsales
Glúteo mayor IM 21G*1 ½
Odontología: 27G-30G inyecciones
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