Summary
Samenvatting antibiotica
- Course
- Institution
overzicht antibiotica (spectrum, farmacologische eigenschappen, resistentie...)
[Show more]
Seller
Follow
Farma505
Content preview
OVERZICHT ANTIBIOTICAANTIBIOTICUM GEBRUIK WERKINGSMECHANISME FARMACOKI SPECTRUM RESISTENTIE- TOXICITEIT/NEVEN-
NETIEK MECHANISME WERKINGEN
Antibiotica die nucleotidesynthese verstoren
Co-trimoxazol inhibitie Breed: G+ & - Gevoeligheid o.b.v.
combi sulfonamide foliumzuursynthese antibiogram
& trimethoprim
Antibiotica die inwerken op nucleotiden
Quinolonen #infecties: respiratoir, inhibitie goede 1e generatie: nalidixinezuur & 1) chromosomale QT-verlenging
F op C6 G(+ en -) intestinaal, urine, huid bacterieel DNA- resorptie, derivaten puntmutatie in DNA FotosensibilisatieAchille
& weke delen, topoisomerase penetratie, 2e generatie: nor/cipro/ofloxacine gyrase spees
been/gewricht, SOA (gyrase) t1/2 > actiever door F 2) effluxpompen GI-flux
inhibitie > G(+ en -)
bacterieel DNA- 3e generatie: Levo/moxifloxacine
topoisomerase 4 > G(+) en pneumococcen (M)
induceren
endonucleasen
Rifampicine TBC Inhibitie transcriptie Penetratie G(+) & mycobacterium Chromosomale Roodkleuring secreten
haemophilius hoog Vd tuberculosis mutaties (urine…)
influenza b
infectie,
stafylokokken
Nitro- Protazoa & anaroob Verbreekt DNA strengen Anaërobe bacteriën & protazoa
imidazolen bact. infecties waardoor transcriptie
blokkeert
, OVERZICHT ANTIBIOTICA
ANTIBIOTICU GEBRUIK WERKINGSMECHANISME FARMACOKI SPECTRUM RESISTENTIEMECHANISME TOXICITEIT/
M NETIEK NEVEN-
WERKINGEN
Antibiotica die eiwitsynthese verstoren
Aminoglycosi Combinatie met B-lactam of Bindt 30S-subeenheid Penetratie G(-) & 1) aminoglyc-inactiverende Nefro-&
den fluoroquinolinen stafylokokken enzymen ototoxiciteit
2) wijziging proteïnen
buitenmembraan
3) verandering thtv ribosoom
Tetracyclines intracellulaire Bindt 30S-subeenheid > - Onopl. chelaten G(+ en -), 1) efflux pompen Cheleren Ca in
Infectie aminoacyl tRNA, met voeding anaëroben 2) ribosomale tanden, diaree,
ziekte van Lyme penetratie door diffusie - lange t1/2 niet beschermingsproteïnen foto, resistentie
Acne 2e generatie: - goede verdeling pseudomonas hoge resistentie bij
mino/doxycycline stafylokokken & streptokokken
Goede opname
Macroliden Luchtweginfectie Bindt 50S-subeenheid > - Inactivatie door Aërobe & anaërobe 1) methylatie 23S rRNA QT, anti-inflam
Macrocyclische Huid- & weke delen blokkeert maagzuur G(+), neisseria, (kruisresistentie)
lactamring ontsteking peptidyltransferase - hoge Vd chlamydia, 2) efflux
campylobacter inf - metabole campylobacter,
chlamydia inactivatie mycoplasma,
trachomatis legionella
urethritis/cervicitis > pneumococ:
helicobacter pylori telithromycine
inf
long > azithromycine
Lincosamide: infecties Bindt 50S-subeenheid > goede verdeling & Aêroob G(+), Methylatie 23S rRNA Diarree door
clindamycine strepto/stafylokokke inhibitie peptidyl resorptie anaëroob G(+ en -) (kruisresistentie met macroliden) clostridium difficile
n transferase (in flora aanw)
menginfecties
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller Farma505. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $5.97. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
67232 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now