Summary Specific immune response OCR A a level notes
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Course
Specific immune response- communicable diseases
Institution
OCR
This document outlines the role of the specific immune response, the different types of cell types that B cells and T cells can differentiate into and their roles , what cell signalling is, the roles of interferons and interleukins in cell signalling. It also provides step by step processes of humo...
The Specific Immune Response Lymphocytes
a defense reactionthat blood cell found in the blood and lymph nodes.
·
A typeofwhite
recognises an antigen ·recognise antigens on the pathogens, and
surface of
and produces antibodies co-ordinate the immune
response againstthe
pathogen-
specificagainst that ·collectively, lymphocytes can
recog nise millions
due bo the
andigen ofdifferent antigens, large variation
Of cymphocytes.
Antigens
Lymphocyte Cell types they differentiate into and roles
haveproteins
called antigensthe
Aces
·
B Cells Enebicononsing anareasan
e
·our immune system is designed to
recognise the difference blower
formed in specific antibodies.
bone
selfand non-sebantigens on pathogens. Develop into is memory cells
Anbigens trigger the immune
marrow which remain in the
response body for years - get as immunologicalmemory
·
an
+mature
co-ordinated by lymphocytes.
·
Antugens are specific to their inecper cells:
T Cells
receasecytokineswhich stimulatebe
pathogen andare usually glycoproteins. so develop the
·
Formed
in bone
I killer cells (cytotoxic cells)
marrow
attack and kill infected host-body cells which
The two responses but display the foreign antigen. Perforin: causes
mature in cells to burst
·
The cell-mediated response
the -memory cells immunological memory.
involveshighly specialised cells that
-
-
chymus
target pathogens inside cens -- system.
· The humoral response targets
Tregulabor cells shut down the immune response
pathogens bodily fluids
-
in with
antibodies offerencemercy,accessfully removed
↑
areinto"hymus gland inside chest wall
, Cell Signalling
B cells and T cells spend most of their lives doing interferon
nothing.
Only when and if they encounter their
released by many cells to,inhibvo
stimulate t
viral replications +
complementary antigen will they be kick started into killer cells.
action. Cell signalling allows a co-ordinated
response by the collective action of all T and B cells.
cytokines
to
interleukins Released by helper cells
stimulate and B cell
+
2 GILL Proliferation + differentration.
cell-signalling
When a pathogen invades the body morecules.
↳ expansion
there are three ways antigens can be
presented to Tand B cells.
I response
cellmediatech
n e e
icels B CeLS- macrophages add the
ppc macrophage antigen on one
B response glycoprotein.
·,
=>
⑧
MHC
antigens
-
gavan in
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