1.4.3 Permissief
= Hormoon moet aanwezig zijn zodat ander hormoon effect kan hebben
Bv: adrenaline heeft enkel effect op energieverbruik als schildklierhormonen aanwezig zijn
1.4.4 Integratief
= Hormonen hebben verschillende, complementaire effecten
Bv: calcitriol en parathyroïdhormoon -> calciumstofwisseling
2. Pancreas (alvleesklier)
Eilandjes van Langerhans:
− Alfa-cellen: glucagon
o Doet cellen glucose vrijzetten uit glycogeenreserve → omgezet in glucose → glycemie
verhoogt
− Beta-cellen: insuline
o Doet cellen glucose opnemen uit bloed → opslaan als glycogeen → glycemie daalt
2.1 Diabetes mellitus: suikerziekte
HYPERGLYCEMIE: extreem hoge glucose concentraties in bloed (>180mg/dl)
2.1.1 Type 1: insulineafhankelijk
− Te weinig insuline synthese
− Jeugdiabetes
− Behandeling: insuline toedienen
2.1.2 Type 2: niet-insulineafhankelijk
− Insulineresistentie: lichaam is ongevoelig voor insuline
− Ouderdomsdiabetes: > 40j, in combi met obesitas
− Behandeling: , aangepast dieet, medicatie
2
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