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NR 603 Week 4 APEA Predictor Exam Review Questions & Answers
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NR 603 Week 4 APEA Predictor Exam Review Questions &Answers
3 Antibiotics
4 Transfusion
5 Bactericidal/permeability-increasing protein
ANS:3 correct answersAntibiotics
Antibiotics are the treatment of choice for meningococcemia. The preferred drug for
active infection is penicillin G. For those allergic to penicillin, chloramphenicol and
cephalosporins (ie, cefotaxime, cefuroxime) may be used as alternatives.
Patients will also receive supportive care, but antibiotic therapy must be initiated quickly
if the patient is to survive. Intensive care placement may be necessary if organ failure is
imminent. Ventilatory support, inotropic support, and IV fluids are necessary in some. If
adrenal insufficiency occurs, corticosteroid replacement may be considered. A central
venous line helps to provide large amounts of volume expanders and inotropic
medications for adequate tissue perfusion.
Steroids have not been shown to play a major role in the treatment of
meningococcemia. However, they have been used in addition to antibiotic therapy. In
the case of adrenal insufficiency, for example, steroid replacement has been shown to
be beneficial.
Transfusion does not generally play a major role in treatment. If the patient suffers from
a devastating coagulopathy, blood or blood products may be replaced as necessary.
Bactericidal/permeability-increasing protein is a protein stored in the granules of
neutrophils. It binds to endotoxin in vitro and neutralizes it. This technique is
experimental, and it is not used in everyday treatment of meningococcemia.
In myasthenia gravis, weakness is a result of insufficient acetylcholine transmission at
the neuromuscular junction; however, weakness can also occur with overdosing of the
cholinergic medications used to treat myasthenia. What symptom helps differentiate a
myasthenic crisis from a cholinergic crisis?
Answer Choices
1 Respiratory failure
2 Bilateral ptosis
3 Muscle fasciculations
4 Diplopia
5 Normal muscle stretch reflexes
ANS: 3 correct answersMuscle Fasiculations
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