Morfología Racimo de uvas, Catalasa +, Coagulasa +, B-hemolítico.
Localización Apertura de las narinas y piel.
Transmisión: por manos, estornudos, heridas quirúrgicas y comidas contaminadas.
Factor de virulencia: Proteína A en membrana plasmática.
Patogénesis
Factores de predisposición: heridas, cuerpo foráneo como tampones y suturas.
Neutropenia, abuso de drogas IV, enfermedad granulomatosa crónica y fibrosis quística.
Inflamaciones: Pneumonía, infiltrado irregular, artritis séptica. Celulitis, impétigo, furúnculos,
absecos eritrematosos, endocarditis agua (válvula tricuspide), osteomielitis.
Patología
Toxinas: Síndrome de piel escalada, Sindrome de shock tóxico (TSS), intoxicación alimentaria
(vómito y diarrea).
Cultivo Agar Sal Manitol: fermenta Manitol (torna el agar amarillo). Colonias doradas en Agar
Diagnóstico
Sangre.
Sensitivos a meticilina: Nafcilina. Resistentes a penicilina: Vancomicina. Adquiere resistencia
Tratamiento
a penicilina alterando proteínas de membrana (MRSA).
Localización Factor de virulencia: streptolisina O (betahem)(anticuerpos ASO), Streptokinasa, y DNasa.
Impetigo (costras de miel), faringitis (strep throat), cellulitis y erisipela (1st). Dolor de garganta,
fatiga, fiebre y dolor de cabeza. Toxina SPE (A<B<C): fiebre escarlata (lengua fresa, faringitis
y rash no en la cara), toxic shock like sindrome, fascitis necrotizante (proteasa B). Fiebre
Patología reumatica (proteina M: Interfiere opsonizacion, mimica molecular miosina “valvula mitral”):
(despues de faringitis), poliartritis, nodulos subcutaneos, eritema marginado y corea de
Sydenhams. Hipersensitividad tipo 2. Glomerulonefritis: orina marron (cola) y edema facial
(empieza 2 semanas despues de cualquier infeccion)
Diagnóstico
Tratamiento Penicilina
J-INCOG
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