Initial treatment of 50 year-old female with metastatic breast CA to ribs & spine with ↑Ca²⁺
Bisphosphonates
[Fluid + Lasix + mithramycine/bisphos/calcitonin/ aldaronic acid]
Contraindications to SLNBx
1. Clinically suspicious axillary LN
2. T3/T4
3. Large biopsy cavity
4. Prior...
ABSITE Review
Initial treatment of 50 year-old female with metastatic breast CA to ribs & spine with ↑Ca²⁺ correct answerBisphosphonates
[Fluid + Lasix + mithramycine/bisphos/calcitonin/ aldaronic acid]
Contraindications to SLNBx correct answer1. Clinically suspicious axillary LN
2. T3/T4 3. Large biopsy cavity
4. Prior axillary surgery
5. Recent mammoplasty/breast implant
6. Likely intraductal papilloma
Young woman with bloody nipple discharge & normal mammogram → correct answerLikely intraductal papilloma → ductal excision
Treatment of breast pain correct answerBromocriptine (inhibits prolactin secretion)
Which is a contraindication to segmental mastectomy or BCT, multicentric disease or pectoralis involvement? correct answerMulticentric disease
ER is a marker for _____ correct answerTumor differentiation
LCIS @ margin of breast excision, NEXT STEP correct answerNo further Rx Tamoxifen & close follow-up
Management of phyllodes tumor (2 cm) correct answerWLE without nodal dissection Management of post-menopausal, ER+, T1N1 (stage IIa) breast CA correct answerChemotherapy + Tamoxifen
Management of melanoma <0.75mm correct answerWLE with 1-cm margins
Management of 1.2mm superficial melanoma without palpable node(s) correct answerWLE with 2-cm margins + SLNBx for all lesions >1.0mm
Management of anal SCCa correct answerChemoXRT (Nigro protocol)
Malignancy most likely to have ascites and carinomatosis correct answerOvarian
Cancer-related cachexia is related to ____ correct answerTNFα
Cancer least likely to metastasize to bone correct answerProstate > Breast > Lung > Kidney > THYROID
Inguinal LN biopsy positive for melanoma with no identifiable primary ... NEXT STEP correct answerCT abdomen/pelvis
Inhibitory factor of tumor growth correct answerTGFβ
Mechanism of angiogenesis correct answerProliferation/migration
Management of 0.8mm melanoma correct answerWLE with 1-cm margins
Which is a more specific tumor marker, β-hCG vs. CA-125? correct answerβ-hCG
Radiation insensitivity in large tumors are 2° to _____ correct answerHypoxia
Submucosal spread of tumor is most common in ______ CA correct answerEsophageal
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