Herpes simplex is a virus that causes skin infections. The infection lasts your lifetime, and it causes painful or itchy sores and blisters that come and go. Herpes simplex virus typically doesn't cause severe problems. But it can be dangerous in infants and people with weakened immune systems
• All DNA viruses
• All enveloped and encapsulated
• All have latency after the initial infection
• Mostly require close contact for transmission
• Human is the only reservoir
• Replication in nucleus of host cell
, Classification
Three subfamily:
(Alphaherpesvirinae),
(Betaherpesvirinae),
(Gammaherpesvirinae)
Alphaherpesvirinae: a lot of hosts, short reproductive
cycle, effective cells (infected ones) destroying, latent
form of existence in ganglia.
Simplexvirus (HSV-1, HSV-2) , Poikilovirus.
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