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samenvatting Histologie: Het steunweefsel of bindweefsel

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Samenvatting van het derde hoofstuk van de cursus van de lector Pascale Dooms aan de Hogent. 4 pagina's. Duidelijk met figuren.

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  • April 24, 2023
  • 4
  • 2022/2023
  • Summary
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Samenvatting histologie: Het steunweefsel of
binweefsel

1. Inleiding
Oorsprong: ontstaan uit mesenchym (embryonaal)

- stervormige samenhangende cellen die ingebed zitten in amorfe intercellulaire
ruimte (later vezels).
- Ovale kernen
- Grote nucleus

Algemene functies: steun, afweer (vb: macrofagen, plasmacellen), voeding (bloedvaten), herstel

Algemene bouw: cellen + ECM (vezels, amorfe grondsubstantie, weefselvloeistof)



2. De cellen
1) Fibroblasten-fibrocyten = bindweefselcel

 Fibroblast:
- Licht stervormig
- Grote ovale kern
- Bleke kern met grote nucleolus
- Secretie van tropocollageen, elastine en intercellulaire grondstof
 Fibrocyt:
- Afgeplatte spoelvormige vel
- Langwerpige kleine kern
- Donker cytoplasma
- Ontstaat uit fibroblast bij inactiviteit

2) Macrofagen

- Door fago-en pinocytose ruimen ze bacteriën en vreemd materiaal op  bescherming
- Amoebe bewegingen voor verplaatsing door het bindweefsel
- Kunnen zich vastzetten
- Kunnen versmelten tot reuzecellen voor grote lichaamsvreemde stoffen

3) Regeneratiecellen

- Lijken op fibroblasten
- Door prikkeling differentiëren in alle mogelijke bindweefselcellen of glas spierweefsel
- Te vinden rond kleine bloedvaten

4) Mastcellen (activatie van het afweersysteem)

- Grote ovale cel
- Cytoplasma sterk basofiel (door granulen): toluïdineblauwkleuring
- Granulen bevatten heparine, histamine en SRS-A
- Oppervlak mastcel met receptoren voor IgE (door plasmacellen gevormd): overgevoeligheid

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