In this file you will find a Rapid Revision Summary by Medic Mukul, for the Pharmacology part of Krok 1. A part of the summary is based on most frequent asked questions as well as ministery questions.
FantamiBlock
ne
-> Diledic act on DCT
-
Hz Stomach
He Reapta vasocialeen
-
-
H ->
e.g Hydrochloodhiazide, Clopamide (4cart)
permeability
↑
vascular
(ptin stomach)
->
causes
Bronchoconstructu Metabolic
-> used
for
Alkalosis
C H I C
CLoose H+)
/Avil
Congestive Hype-Insipidus Calculi
Diphenyl hydramine
I
Dimedro / Heart Tension (Diabet)
I
S
S/E-Sedation (moe
Tavegil ↳
Supzastin
Sleep) Neven
give with
Digioxin
↓
Give Loadidine-2ndG. Potassium
Sparing Divatics -> Acton Collecting duct
3rd-No sedation Citzizine less Sedative. 1) Spizinolactone Antagonistof
=
Aldostenone
↳ Levo -Citzzine & Des-losatidine ->
used for CONN' Syndrome
->
Best for CHF
↳
hyperaldostenonism
↳ * Nat ↑
cat
kt
S/E-Gynecomastia
↓
->
Succinyl Chdine AKA
=
Didhylinum a Listenone 2) Eplizenon - cause
doesn't
Gynecomastia
(non-competitive/izreversible)
4
Depolarising Muscle Relaxant (shatpa). I potasium sparing Davetics
↳ La Tracheal
I
Used Indubation A
-
Amiloride
inhibited Spizinolactone
by pseudocholinestease S -
or
class I ↳ SIE-SLE (systemic Lupus Ezythematous
↳ mechanis of Action;Binds to heuromic Receptas of CNat
(MM0A)
parasymp.Cflaccid paralysis)
Myastemia -
in Muscle
Result
Lading Blocke) Lidocai -> Both Anesthetic aswell as Avrythmic
procain
Doc faMI & Digoxin toxicity
Gavis
->
induced VT
novocain
↳Antidote
Audoimmune
disorder (Drug of CHoise)
-
Neostigamin
(adnozecptas)
I Mepse or
-> Beta Blockens
Class I symp.
-> DOC fa Atrial fibzillation/Atzial Flut
, Minna Mamik
class I
[Amiodzone ->
longestadding A-arythmic Opoids
MOA:Ktchannel
by Natural opoids:Morphine
->
Blocken,
prolong Repolarisation codeine
Moscapine
Class
(Butiazem cantchannel Black herag en Semi Synthetic -> Heroine (Diacetylmaphine)
Stable Angina
Synthetic opoids ->
Fentaryl -> loox
m ore powerfull then maphine
Calcium Channel Blockus function of uses:
in
Epilepsy abnormal Neucoleptic Anal gesia
↳ Brain du do GABA
Sodium Anaesthesia
1) Valpzoate
-Cart channel+Nat channel Blockers Opoid Agonist -> acton opoid Recepta
killer
GABA -> pain
↳
inhibits neurot. , ↑ GABA
by inhibiding its metabolism Morphine->Analgesic fa Seven pain (Labour, cance, MI)
use for kids
can't
↳4 Histamine
- ist line
drug fa Epilepsy (Scizures) zelease
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