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Summary Microbiology Rapid Revision Krok 1 $3.23
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Summary Microbiology Rapid Revision Krok 1

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  • Course
  • KROK-1, USMLE Step 1
  • Institution
  • KROK-1, USMLE Step 1

In this file you will find a Rapid Revision Summary by Medic Mukul, for the Microbiology part of Krok 1. A part of the summary is based on most frequent asked questions as well as ministery questions.

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Document information

  • May 2, 2023
  • 8
  • 2022/2023
  • Summary

Subjects

  • krok 1
  • usmle step 1
  • krok 1
  • krok exam
  • ua medical exam
  • general medicine
  • dentistry
  • ukarine medical exam
  • krok microbiology base
  • krok microbiology summary

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  • KROK-1, USMLE Step 1
All documents for this subject (9)

1  review

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By: harmdhal • 4 months ago

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minoo

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Microbiology
Rapid Revision KROK




Minna Mamik
@ Medic Mukul

, Salmonella dyphi Mycobacterium Tuberculi TB
(NON MSC)
-




-




G
/Enteric Fever Gram *, NON-motile, Non-spoce, Non-Capsulated
=>

Typhoid Fever S




affect
-
Small intestine -> cause Maration >Acid Fastresistant - Carbon Fusain Stain (fa acidfast)
-Test;Widal Test (Tube agglutination dest) -Stain -
Ziel Nelson
staining
Diagnosis -
B-Blood Culture (stweek) >Medium-Lowenstein
Zensen Medium (Growth-medium)

Diagnosticum A
Agglutination (2nd werk) ~Cell Wall
Mycolic acid
= -
-




Test
BASU S-Stool Culture (3rd week) >Culture -
Gold standard fa Diagnosis ofTB
U-Uzine Culture (tweek) Miliary TB -




extrapulmonary Spread
>Motile (0& Handigen), Gro ↑TB -




Mainly Middlec Lower Lobe affected
-Seroidentification Agglutination with Diagnostic Serum 2"TB
Mainly affectupper lobe
late
-
=




Salmonella -> Colorless colonies

↳ But
on Bismuth Sulfite Agar=> Black colonies Tuberculoma- Round formation san friable mass
↳
Widal testRadio; 1:20 ->
Repeattest after 10
days Secondary form with Capsule formation
of TB
small intestive Typhi
1:00 Carrier of Salmonella >Giant (No capsule formation)
macrophage zegular TB
In
->




s 1:400 ->
Diagnosed ->

Tyhd
e >Caseous Necrosis

Large Intestine Dysentzial Hashoe Nuclei


Shigella dysentrial Langerhan cell Granuloma (Giant
microphage)
↳ adaptive
appropriate
determine
immune
↳
Dysentry -


AffectLarge Intestine
(usually Colon) response (inflammation or tolerance)
infection
Help body fight
>Non-motile, Gr

.
Complications;· Hemoytic Unemic Syndrome (HUS) Test faTB -
Mantoux/Tuberculin test
Stype I
hypesensitivity)
·

Hemorhagic cystilis -Deparation -
Tuberculin



-injectade
How


Amoebic
Dysentzy (A morbiasis) papule famation
↓
No Papule famadion
↓
↳ Caused
by Entamoeba histdytica Immunity pt.
Immunityabsent
↓
-
Raspberry stoo >intestinal disfunction NOTB
TB
& pain
>Pseudopodia (False feet) Fa TB ->
Spudum culture ASTMG
(Homogenisation method) ↳ Charlotte
Leydig cell
-Cyst has 4 nuclei -
Erythrocytes in
cytoplasm &
zound Curschmann's Spiz
>Feces, mucus & Blood Vaccine -
BCG Guein)
(Bacillus Calmate

vibzio Cholera Treatment -
DOTS (Directly Short Ten)
Observed Treatment

Gr, 1st line
>Motile, Comma shaped, Curved Daugs
Rif;
>Produce Endeotoxin R -



Rifampiain -> Inhibits mRNA cause zeddish-Ozange

Grow 14
in Alkaline Peptone Booth I -


Isoniazid- HVitBs, Peripheraldanseneat a Ate

Neuropathy
Activate
enzyme adenylate Cyclase enzyme p pyzazinamide ->4 Uric Acid (Gout)
-




↳4
CAMP in intestine
Ethanol Optic
Eye E -> Neuritis
-




Rice water
stool-201 water loss S-Steptomycin Hearing loss, damages
>
-
hair
calls

-Sunal
>Isoosmolar Diarchea (Noodom) ↳ Doesn't
supress synthesis of cell wall

of bacteria.
->
Treatment; ORS +



Tetracycline
CORAL Dehydzation Sallt)
-> Fecol-cal Transmission (water)

kw,:"hangin drop" preparation by phase contrast Microscopy



Minna Mamik

, Spizochetes -
Borelia

-Treponema pallidum >Gr, regular Spirals
Leptospira Interrogans -Cause
Relapsing Feren

>Borrelia >Diagnosis:Wetmount a
phase Contrast
o Dark Ground Microscopy

Tzeponema
-




-Lyme Disease:MC caused
by B. burgdaferi
>Gram ↳ vector Hard dick (Ixodid)
& Spiral shaped 10-14 microns long, -




Cakscrew motility
Tapening ends,

Intracellular
Obliquate (Not cultivated on Cellfue Med.) Relapsing Fever
Syphilis
Demonstrated Dark field Microscopy Giemsa Giemsa
by
-
-




Silver Strains
Impregnation -
S-7
large curs -
12-14 large Grols

↳ Primary Syphilis -



painless wer -



10-30RM long
-

10-13 pum
long
Secondary Syphilis -



Maculopapulan
A symptomadic
Rash -
Bluish-Vichetcolour -




lightpink/Rose Colo




Escherichia Coli
Terdiary Syphilis -
Gumma bodies seen


Nemosyphilis Surface Andigen 0.111


=>
Test fa Syphillis >Cause Coli enteridis

·
Immobilization Reaction Test ~Medium Endo
agar
-




·
Endovasculitis & Perivasculitis >Red Colonies (Salmonella-couless)

Diagnosis of Syphillis
at ego
colitite e
=




Microscopy- Early syphilis
Seology Mc used
-
Coliindex
Quantity proportional
-
to Actual content of E.coli
in 1L water
Wasserman test -> isttest Introduced for Syphilis OR

colony of
ptin
water
1
↳ Fixation
It's Complement Test Assume 4colonies


Treatment; Bismuth o
Benzyl Penicillin G
ScarletFever -


Streptoccus pyogens Gre

-




Leptospira interiogans >Type I
Hypersensitivity
Red
, GrO, Spiral Shaped (casa? Strawberry on Crimson coloured tongue (covered with
S exceptfor nasolablial triangle C yellow -




whaat
>Shephered Glock
appearance -Sand paper like ash


>Umbrella Handle appearance Circumoralpalla &
Erythemadous checks



Microscopy -> Dark Ground Minoscapy >pastia lines

Silver
Impregnation Stains Treatment:Penicillin


leptospinosis periodically pt. of
in Wine Reservoir
↳ Rats & Rodents
Treatment; Denicillin & awasakiDisease
Doxycycline *


jaundice ↳ Autoimmune




Conjuctival
WERS
TRIAD-
pain in
~Rash


Prolonged fever
on hand & feet
&
Conjuctivitis in child


Hemohage calf muscle >Treadment:Aspirin
(M. Gastriconemius)




Minna Mamik

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