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Samenvatting Overzicht Geneesmiddelen - Farmacologie (D012577A) & (J000507A) $7.60   Add to cart

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Samenvatting Overzicht Geneesmiddelen - Farmacologie (D012577A) & (J000507A)

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Overzicht van alle besproken geneesmiddelen in de lessen van Prof. L. Devisscher en Prof. S. Lefere. Werkingsmechanisme, effecten, indicatie en bijwerkingen overzichtelijk weergegeven voor alle geziene geneesmiddelen. Gebaseerd op slides + eigen notities.

Last document update: 1 year ago

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  • May 16, 2023
  • May 27, 2023
  • 38
  • 2022/2023
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2  reviews

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By: emelieteirlinck48 • 6 months ago

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By: annelienvandevelde • 1 year ago

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A UTONOOM ZENUWSTELSEL

Geneesmiddelen i.v.m cholinerge transmissie (Ach → nicotine / muscarine receptoren)
Geneesmiddel Werkingsmechanisme Effecten Indicaties Bijwerkingen
Hart: HF daalt contractiekracht
1. Muscarine agonisten ⁎ Glaucoom (pilocarpine)
Bloedvaten: VD
(parasympathicomimetica) Selectieve stimulatie van
⁎ Blaasatonie (bethanechol)
muscarinereceptoren Exocriene klieren: meer secretie
Pilocarpine ⁎ Droge mond (Pilocarpine)
Oog: myosis, daling oogdruk, accommodatie
Bethanechol (radiotherapie, Sjörgen)
GS (≠Buiten BV): contractie

⁎ IBS = Darmkrampen
⁎ Overactieve blaas
Hart: HF stijgt
2. muscarine antagonisten ⁎ Parkinson (tremor↘) Bij intoxicatie:
(parasympathicolytica, Bloeddruk: niets → NIET cholinerg bezenuwd ⁎ Organofosfaten
Competitief antagonisme van ⁎ Nausea braken (reizen)
anticholinergica) + Pralidoxime
muscarinereceptoren GS (≠Buiten BV): relaxatie
⁎ COPD, astma
(meestal niet-selectief) ⁎ Paddenstoel
Atropine Exocriene klieren: minder secretie
Buthylhyoscine bromide Atropine: met muscarine
Oog: mydriase, oogdruk ↗, verstoring accomm
⁎ Oftalmoscopie
⁎ Bradycardie
⁎ Premedicatie (anesthesie)

3. Niet-depolariserende
tegengegaan dr
Neuromusculaire blokkers Competitief antagonisme van
⁎ Anesthesie cholinesterase-
nicotinereceptoren thv Verslapping dwarsgestreepte spieren
inhibitoren
Tubocurarine neuromusculaire eindplaat niet voorafgegaan door spiertrekkingen ⁎ intensieve zorgen (+ atropine~controle
Atracurium → Reversibel !
cholinerge effecten)
Cisatracurium

4. Depolariserend Agonisme van nicotine Verslapping dwarsgestreepte spieren NIET tegengegaan dr
neuromusculaire blokkers receptoren thv NM eindplaat wel voorafgegaan door spamsen ⁎ Anesthesie (korte ACh – inhibitoren
→ verlengde depolarisatie procedures)
Suxamethonium → verlies elektr exciteerbh Kortwerkend Spierpijn

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