2023 RxPrep NAPLEX Course Book Mnemonics and Pearls Helpful and pertinent mnemonics and pearls gathered from the RxPrep 2023 version of the NAPLEX Course Book Pearl - Amide - vs. Ester -Type Anesthetics - ANS-Amide -type anesthetics can be recognized by the "i" in their name before the" -caine" ending (e.g., lidocaine, bupivacaine, mepivacaine, ropivacaine). Ester -type anesthetics do not contain an "i" before the " -caine" ending (e.g., procaine, benzocaine, cocaine, tetracaine). Hypersensitivity to on e type of drug in an anesthetic class, such as the ester -type procaine, does not confer cross -reactivity to drugs within the opposite anesthetic class, such as the amide -type lidocaine. Mnemonic - SLUDD - ANS-Parasympathetic Nervous System Physiologic Res ponse Salivation Lacrimation Urination Defecation Digestion Mnemonic - G-PACMAN - ANS-Common CYP - Inhibitors Involved in Drug Interactions Grapefruit Protease Inhibitors (especially ritonavir) Azole Antifungals (fluconazole, itraconazole, ketoconazole, vo riconazole, etc.) Cyclosporine, cobicistat Macrolide Antibiotics (clarithromycin, erythromycin, not azithromycin) Amiodarone (and dronedarone) Non-DHP CCBs (verapamil, diltiazem) Mnemonic - PS-PORCS - ANS-Common CYP - Inducers Involved in Drug Interactions Phenytoin Smoking Phenobarbital Oxcarbazepine Rifampin, rifabutin, rifapentine Carbamazepine St. John's wort Mnemonic - Salty Buns & Pot of Coffee with Cream and Sugar - ANS-Stick Diagram for BMP Na Cl BUN Glucose K HCO3 SCr Pearl - "Color" Drug References - ANS-Red Book (Pharmacy) - Drug pricing information Red Book (AAP) - Summaries of pediatric IDs, antimicrobial treatments, and vaccinations Pink Book (CDC) - Information on e pidemiology and vaccine -preventable diseases Pink Sheet (Pharma Intelligence) - News reports on regulatory, legislative, legal, and business developments Orange Book (FDA) - List of approved drugs that can be interchanged with generics based on therapeutic equivalence Yellow Book (CDC) - Information on the health risks of international travel, required vaccines, and prophylactic medications Green Book (FDA) - Information on approved animal drug products Purple Book (FDA) - List of biological products and bio similars Mnemonic - Please Let Greg Brown Bring Peaches To Your Wedding - ANS-Warfarin Tablet Colors Pink (1mg) Lavender (2mg) Green (2.5mg) Brown (3mg) Blue (4mg) Peach (5mg) Teal (6mg) Yellow (7.5mg) White (10mg) Pearl - Warfarin Dietary Supplements/Food Interactions ("the 5 G's") - ANS-Increase Bleeding Risk - "the 5 G's" (garlic, glucosamine, ginseng, gingko, and ginger), dong quai, vitamin E, evening primrose oil, high doses of fish oils, grapefruit, willow bark , and wintergreen oil Decrease Bleeding Risk - St. John's wort, green tea, coenzyme Q10, and foods high in Vitamin K (spinach, broccoli, brussel sprouts, cabbage, kale, collard greens, cauliflower, canola oil, chickpeas, cole slaw, etc.) Mnemonic - CHA2DS 2-VASc Scoring System - ANS-Estimation of the risk of stroke in atrial fibrillation/flutter CHF (1 point) HTN (1 point) Age greater than or equal to 75 years (2 points) Diabetes (1 point) Stroke/TIA history (2 points) Vascular disease (prior MI, PAD, aort ic plaque) (1 point) Age 65 -74 years (1 point) Sex category, female (1 point) Score greater than or equal to one (males) or two (females) are at moderate risk for stroke and anticoagulation may be considered
