CITI Training: Questions With Solutions
Which of the following are the three principles discussed in the Belmont
Report? ✔️Ans - Respect for Persons, Beneficence, Justice
Which of the following is an example of how the principle of beneficence can
be applied to a study employing human subjects? ✔️Ans - Determining
that the study has a maximization of benefits and a minimization of risks.
The Belmont Report's principle of respect for persons incorporates at least
two ethical convictions: first, that individuals should be treated as
autonomous agents, and second, that: ✔️Ans - Persons with
diminished autonomy are entitled to protection.
Subjects with a serious illness may be at risk for exploitation because they
may be desperate for a possible cure. This is an example of: ✔️Ans -
Medical Vulnerability
Identify the following groups that are protected in the federal regulations (45
CFR 46), specifically in Subparts B, C, and D with additional protections:
✔️Ans - Pregnant women, prisoners, children
Which is an example of a situation where deferential vulnerability might be a
factor? ✔️Ans - A physician recruiting his patients
When an IRB is reviewing a research study and they are considering if a
potential subject population is vulnerable, they should consider: ✔️Ans
- Is there a power differential between researchers and subjects?
A subject participates in a drug study because treatment is available at no or
reduced cost, and he could not otherwise afford it. This is an example of:
✔️Ans - Economic vulnerability
The Belmont principle of beneficence requires that: ✔️Ans - Potential
benefits justify the risks of harm.
, According to the Belmont Report, the moral requirement that there be fair
outcomes in the selection of research subjects, expresses the principle of:
✔️Ans - Justice
Which of the following studies is linked most directly to the establishment of
the National Research Act in 1974 and ultimately to the Belmont Report and
federal regulations for human subject protection? ✔️Ans - The Public
Health Service Study of Untreated Syphilis
The researcher's failure to protect research subjects from deductive
disclosure is the primary ethical violation in which of the following studies?
✔️Ans - "Tastes, Ties, and Time (T3)" study (2006-2009)
Which of the following is an example of how the principle of beneficence is
applied to a study involving human subjects? ✔️Ans - Ensuring that
risks are reasonable in relationship to anticipated benefits
According to the federal regulations, human subjects are living individuals
about whom an investigator conducting research obtains information through
interaction or intervention with the individual, and uses, studies, or analyzes
the information; or: ✔️Ans - Obtains, uses, studies, analyzes, or
generates identifiable private information.
According to the federal regulations, which of the following studies meets the
definition of research with human subjects? ✔️Ans - An experiment is
proposed on the relationship between gender-related stereotypes in math and
the subsequent performance by males and females on math tests.
According to the federal regulations, which of the following studies meets the
definition of research with human subjects? ✔️Ans - A cognitive
psychologist enrolls undergraduate students for a computer-based study
about the effect of mood on problem-solving behaviors.
A medical record is an example of ✔️Ans - Private information
Census data (the final report as published by the Census Bureau) is an
example of: ✔️Ans - Public information
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