Summary
Summary Sterilisation kinetics
- Course
- Institution
Industrial pharmacy - 1st semester Includes bullet points, key diagrams and images
[Show more]
Seller
Follow
alexd1
Content preview
Sterilisation Kinetics All follow first order kinetics
Rate of death at a specific time is dependant on the number of micro-organisms
present
Kinetics
N0=number of microbes present at t=0
Nt=number of microbes present at t
First order decay dN/dt=-constantxN 0
log(Nt)=log(N0)-kxt (k=constant/2.303)
k is a specific value for each microbe at each temperature
Half Life
Must have t=t1/2 and Nt=0.5xN0
t1/2=0.301/k and is independent of N0
Decimal Reduction Time (D)
D is the time to reduce the bioburden to 10% of its initial value (in minutes)
t=t0.1 which is D and Nt=0.1xN0
D=1/k
D is independent of N0
D value is related to particular micro-organism and temperature
At 121o D tends to be between 0.5-2 minutes
D can predict how long it will take to reduce the number of micro-organisms to a
specific level or by a specific amount
Temperatures Effect on D
As temperature increases D decreases (not linear)
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller alexd1. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $3.97. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
84146 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now