PEBC EE Q&As with complete solution graded A+ 2023

PEBC EE Q&As with complete solution graded A+ 2023 Thiazide Diuretics AEs 'MICH' -Metolazone -Indapamide -Chlorthalidone (thiazide-like) -HCTZ - correct answer -Impotence -Hypokalemia (inc DIGOXIN toxicity) -Inc Urate (CI in Gout) -Inc BG (CI in DM, lowers antihyperglycemic effect of drugs) -Inc Lipids -Hypotension (effect lowered by NSAIDs) *not effective in renal dysfunction Regulators of Body Temperature - correct answer -urine -skin -sweat glands Teratogenic Drugs cause damage during? - correct answer 2nd- 8th week Components in saliva? - correct answer Lysozyme, IgA, Amylase Factors responsible for transfer of drug across placental barrier - correct answer Conc of drug Molecular size of drug Drug solubility Derived from Tryptophan? - correct answer Niacin, Melatonin, ~5-HTP~5-HT (serotonin) Tx thrombocytopenia - correct answer Oprelvekin (IL-11) Iron - correct answer -most abundant metal in the body -excess: hemochromatosis -antidote OD: deferoxamine Epinephrine derived from? - correct answer Phenylalanine-Tyrosine-Dopa-Dopamine-NE-EPI Aminoglycoside SEs: 'AMINO' - correct answer Allergy M neuroMuscular blockade Inactivated when physically mixed with B-lactams Nephrotoxicity Ototoxicity, Optic nerve toxicity Lifespan of RBC - correct answer 120 days Lifespan of Platelets - correct answer 7-10 days Most abundant WBC - correct answer Neutrophils 60% RBC sequence of cells - correct answer Hemocytoblast-Megaloblast-Erythroblast (normoblast)-reticulocytes-erythrocytes