Edexcel A Level 2022 papers and
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Candidate surname Other names
Centre Number Candidate Number
Pearson Edexcel Level 3 GCE
Time 2 hours 30 minutes
Paper
reference 9BI0/03
Biology B
Advanced
PAPER 3: General and Practical Principles in Biology
You must have: Total Marks
Scientific calculator, HB pencil, ruler
Instructions
• Use black ink or ball-point pen.
• centrethe
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• Answer all questions.
• Show your working in any calculation questions and include units in your answer
where appropriate.
• Answer the questions in the spaces provided
– there may be more space than you need.
• You may use a scientific calculator.
• toIn question(s) marked with an asterisk (*), marks will be awarded for your ability
structure your answer logically, showing how the points that you make are
related or follow on from each other where appropriate.
Information
• The total mark for this paper is 120.
• The marks for each question are shown in brackets
– use this as a guide as to how much time to spend on each question.
Advice
• Read each question carefully before you start to answer it.
• Try to answer every question.
• your answers if you have time at the end.
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Write your answers in the spaces provided.
1 Nerve impulses are transmitted along neurones.
(a) (i) In the time period between two nerve impulses, the potential difference
across the membrane is –70 mV.
State the term given to this potential difference.
(1)
(ii) When the neurone is stimulated, an action potential may occur in the axon,
due to the change in permeability of the membrane to ions.
The graph shows an action potential.
+50
+30
+10
Membrane –10
potential / mV –30
–50
–70
–90
0.5 1.0 1.5 2.0 2.5
Time / ms
Describe what happens in the axon membrane to cause the change in
potential difference between 0.55 ms and 0.80 ms.
(4)
, (b) Scientists investigated the effect of stimulating an axon with different voltages
and measured the response.
The table shows the results of this investigation.
Stimulus voltage / mV Response
25 No action potential
35 No action potential
45 No action potential
55 Action potential
65 Action potential
75 Action potential
Analyse the data to describe the conclusions which can be drawn.
(2)
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