Neoadjuvant therapy does not increase survival when compared to adjuvant therapy. It only changes the timing of treatment and can change surgical options if the tumor is shrunk enough. If this occurs, the patient may only require a lumpectomy plus radiation therapy instead of needing a mastectomy -...
nutritional status, polypharmacy, and a medication review (NCCN Older Adult
Oncology Guidelines, version 1.2015). - CORRECT ANS Due to Mrs. Turner's
age and comorbidities, her oncologist performs a comprehensive geriatric
assessment. You know that this assessment covers all but which of the following:
65 - CORRECT ANS The NCCN Older Adult Oncology Guidelines (version
1.2015) provides information on what is included in a comprehensive geriatric
assessment. Currently, more than 60% of cancers in the United States occur in
people age ______and older and as the oncology world ages, nearly half (46%) of
cancer survivors are 70 years of age or older
Two of the agents (docetaxel and carboplatin) that Mrs. Turner will receive are
categorized as irritants. Docetaxel can cause a significant reaction if it
extravasates. It can lead to edema, erythema, occasional pain and blister formation
(ONS Chemo/Bio guidelines, 2014). That is the most likely reason that Mrs. Turner
,ONS ONCC CHEMO RENEWAL 2023
QUESTIONS AND ANSWERS100%
VERIFIED AND GRADED A+
was given a port for her treatments. Some patients will receive their treatments
through a peripheral IV without incident. Just because they are intravenous agents
does not mean that a port is required and needing a port has nothing to do with her
being older in age. Since none of these agents are vesicants, they likely could have
been given safely via peripheral route but having a port placed is OK as well. -
CORRECT ANS What is your best explanation for why Mrs. Turner was given a
port to receive her chemotherapy?
Irrirtants - CORRECT ANS _____________can cause inflammation, pain, and
burning but rarely cause tissue necrosis comparable to a vesicant (unless a large
amount or a very high concentration of the irritant is extravasated).
Vesicants - CORRECT ANS _____________can cause blistering and significant
pain and tissue damage and destruction, leading to tissue death.
Non-DNA-binding solutions remain in the local area of the extravasation, which
improves the possibility of drug deactivation.
DNA-binding agents attach to DNA nucleic acids, causing the antagonist to be
ingested cellularly, leading to progressive tissue destruction - CORRECT ANS A
further classification of an antineoplastic agent's potential to cause damage is
whether its mechanism of action includes DNA binding.
Bendamustinea
Dactinomycin
Daunorubicin
Doxorubicin
, ONS ONCC CHEMO RENEWAL 2023
QUESTIONS AND ANSWERS100%
VERIFIED AND GRADED A+
Epirubicin
Idarubicin
Mechlorethamine
Mitomycin - CORRECT ANS DNA Binding Irritants
Amsacrine
Paclitaxel
Vinblastine
Vincristine
Vindesine
Vinorelbine - CORRECT ANS DNA Nonbinding vessicants
Sodium thiosulfate
Inject 2 ml of sodium thiosulfate for each milligram of
mechlorethamine extravasated.
Inject subcutaneously into extravasation site using a 25
gauge or smaller needle (change needle with each injection).
Monitor extravasation site according to the institution's
policies and procedures. - CORRECT ANS Extravasciation Alkylating /
Mechlorethamine tx
Apply warm compresses.
Dexamethasone
8 mg twice daily
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