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Zeer uitgebreide samenvatting van embryologie waar iedere hoorcollege uitgebreid in is uitgewerkt

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Dit is een zeer uitgebreide samenvatting van embryologie waar elke ontwikkeling en afwijking tot aan de kiembladen is uitgelegd. Ieder hoorcollege is zorgvuldig uitgeschreven.

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  • June 28, 2023
  • 175
  • 2022/2023
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Embryologie en teratologie



EMBRYOLOGIE EN TERATOLOGIE


Inhoudsopgave
Inleiding – Voortplanting .................................................................................................................. 5

Praktische informatie .................................................................................................................... 5

1.1 Inleiding ................................................................................................................................... 5

1.2 Spermato- en spermiogenese ............................................................................................ 10

1.3 Vrouwelijke ontwikkeling...................................................................................................... 13

1.4 Hormonen .............................................................................................................................. 17

Bevruchting – Klieving – Gastrulatie.............................................................................................. 18

2.1 Bevruchting ........................................................................................................................... 18

2.2 Abnormale bevruchting ...................................................................................................... 19

2.3 Klievingsdelingen .................................................................................................................. 22

2.4 Ontstaan van zygote/ blastomeer / morula/ blastula/ blastocyst ................................ 24

2.5 Abnormale klieving .............................................................................................................. 25

2.6 Blastulatie .............................................................................................................................. 29

2.7 Gastrulatie ............................................................................................................................. 31

2.8 Ontstaan notochord ............................................................................................................ 33

2.9 Differentiatie mesoderm ...................................................................................................... 34

2.8 Fouten bij de gastrulatie ...................................................................................................... 35

Primitieve lichaamsvorm ................................................................................................................ 36

3.1 Neurulatie (vorming neurale buis) en drie-dimensionele structuur ............................... 36

3.2 Drie-dimensionele structuur ................................................................................................. 37

3.3 Differentiatie van lateraal-plaat mesoderm ..................................................................... 37

3.4 Neurale buisdefecten (NTD’s): ............................................................................................ 38

3.5 Primitieve lichaamsvormen ................................................................................................. 40

3.6 Differentiatie paraxiaal mesoderm .................................................................................... 41


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, Embryologie en teratologie


3.7 Differentiatie ectoderm ....................................................................................................... 42

3.8 Differentiatie intermediair mesoderm ................................................................................ 42

3.9 Vorming coeloomholte........................................................................................................ 43

3.6 Vorming linker en rechter hartbuis ..................................................................................... 45

Ontwikkeling GI ............................................................................................................................... 47

4.1 Aanleg gastro-intestinaal stelsel (maag-darm) ................................................................ 47

4.2 Aanleg oerdarm / darm ...................................................................................................... 50

3.4 Aanleg mondholte ............................................................................................................... 51

3.5 Fouten aanleg mondholte .................................................................................................. 53

3.6 Aanleg neus .......................................................................................................................... 53

3.7 Aanleg wangen en tandvlees ............................................................................................ 54

3.6 Aanleg tanden en lippen .................................................................................................... 55

3.6 Aanleg gehemelte ............................................................................................................... 56

3.8 Fouten aanleg mondholte .................................................................................................. 57

3.7 Aanleg tong .......................................................................................................................... 59

3.9 Aanleg schildklier (Thyroïd).................................................................................................. 60

3.10 Aanleg gehoorgang .......................................................................................................... 61

3.10 Samenvatting kieuwbogen ............................................................................................... 62

3.11 Thymus en parathyroïd (bijschildklieren) ......................................................................... 66

3.12 Slokdarm / Oesophagus .................................................................................................... 67

3.12 Aanleg maag ..................................................................................................................... 68

3.13 Aanleg darmen .................................................................................................................. 69

3.14 Afwijkingen aanleg darmen ............................................................................................. 70

3.15 Aanleg milt .......................................................................................................................... 71

3.14 Aanleg lever ........................................................................................................................ 72

3.14 Aanleg klieren ..................................................................................................................... 73

3.15 Aanleg pancreas ............................................................................................................... 74

Ontwikkeling Ademhalingsstelsel .................................................................................................. 75

4.1 Aanleg neus .......................................................................................................................... 75

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, Embryologie en teratologie


4.2 Aanleg longen ...................................................................................................................... 77

4.3 Aanleg pleura ....................................................................................................................... 80

4.4 Aanleg diafragma................................................................................................................ 81

Placentatie ...................................................................................................................................... 83

5.1 Belangen van placenta ...................................................................................................... 83

5.2 Uterus ..................................................................................................................................... 83

5.3 Cyclus van endometrium .................................................................................................... 84

5.4 Bevruchting of niet? ............................................................................................................. 85

5.5 Aantal en duur ovarium cyclus........................................................................................... 85

5.6 Implantatie ............................................................................................................................ 86

5.7 Differentiatie van het trophoblast ...................................................................................... 88

5.8 Functie van de placentatie ................................................................................................ 89

5.9 Grondplan placenta bij de huisdieren .............................................................................. 90

5.10 Vorming van placenta ...................................................................................................... 91

5.10 Placenta types .................................................................................................................... 93

5.11 Opbouw placenta syndesmochorialis ............................................................................ 96

5.12 Pathologie van de placenta ............................................................................................ 97

5.13 Embryonale aanhangsels .................................................................................................. 97

Ontwikkeling CV-lymfe ................................................................................................................. 103

6.1 Aanleg van het hart ........................................................................................................... 103

6.2 Aanleg aortabogen ........................................................................................................... 109

6.3 Aanleg bloedvaten............................................................................................................ 111

6.4 Afwijkingen aan het hart ................................................................................................... 114

Ontwikkeling van het lymfestelsel ............................................................................................... 115

6.5 Lymfevaten, lymfeknopen en lymfefollikels .................................................................... 115

6.6 Aanleg leversinusoïden – bypass...................................................................................... 117

Bewegingsstelsel ........................................................................................................................... 118

7.1 Algemeen ............................................................................................................................ 118

7.2 Ontwikkeling skelet ............................................................................................................. 120

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, Embryologie en teratologie


7.3 Ontwikkeling van de schedel – complex! ....................................................................... 121

7.4 Ontwikkeling wervels .......................................................................................................... 122

7.5 Ontwikkeling ribben ........................................................................................................... 122

7.6 Vorming ledematen ........................................................................................................... 123

7.7 Afwijkingen van het skelet ................................................................................................. 123

7.8 Ontwikkeling gewrichten ................................................................................................... 124

7.9 Congenitale afwijkingen gewrichten .............................................................................. 125

7.10 Ontwikkeling spieren ........................................................................................................ 125

7.11 Spieren huid ...................................................................................................................... 127

Zenuwstelsel – Oog – Oor............................................................................................................. 128

8.1 Zenuwstelsel Algemeen ..................................................................................................... 128

8.2 Afwijkingen ruggenmerg ................................................................................................... 130

8.3 Vorming van hersenblaasjes ............................................................................................. 132

8.4 Afwijkingen hersenaanleg ................................................................................................. 132

8.5 Differentiatie van neurale lijst .................................................................................................. 133

Ontwikkeling van het oog ........................................................................................................... 135

9.1 Algemeen ............................................................................................................................ 135

9.2 Afwijkingen aan het oog ................................................................................................... 141

9.3 Ontwikkeling van het oor .................................................................................................. 142

9.3 Afwijkingen van het oor ..................................................................................................... 144

Urogenitaal stelsel deel 1 ............................................................................................................. 145

10.1 Algemeen .......................................................................................................................... 145

10.1 Ontwikkeling nieren .......................................................................................................... 146

10.2 Ontstaan urogenitale sinus .............................................................................................. 150

10.3 Ontwikkeling urineblaas................................................................................................... 151

10.4 Congenitale afwijkingen van de nier en de urinewegen ........................................... 153

Urogenitaalstelsel Deel 2 .............................................................................................................. 154

11.1 Indifferent stadium ........................................................................................................... 154

11.2 Differentiatie vrouwelijk genitaal stelsel ......................................................................... 157

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