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GCSE Biology Nervous System GRADE 9 Notes

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GCSE Biology Nervous System GRADE 9 Notes as part of the Homeostasis topic

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The Nervous System
 The nervous system is divided into two parts:
o Central Nervous System: Brain and Spinal cord
o Peripheral Nervous System: all other nerves of the body
 Nerve cells (neurones) carry electrical impulses
o Very fast transmission, unlike hormones

Structure of Neurons
 We had a look at the structure of nerves – there is a dendrite, cell body, axon, and the nerve ending. Like a
normal cell, we have cytoplasm, a cell membrane and a nucleus in the cell body.
 When an impulse is generated, it travels down the neuron, from the dendrite to the nerve ending down the
axon.
 At the nerve ending, the neuron communicates with muscles, glands, or other nerves via synapses.
 One nerve contains multiple neurons, wrapped in connective tissue.
 The axon is made of the myelin sheath, which itself is made up of Schwann cells, with nodes of Ranvier in
between. The myelin sheath insulates the neuron.
o Intervals in the sheath are nodes of Ranvier – parts of the axon not covered in myelin. These gaps
allow the rapid transmission of electrical impulses – the impulse doesn’t need to travel the whole
length of the axon – it can ‘jump’ between the nodes of Ranvier (where there is no myelin) as the
impulses cannot pass through the myelin. speeds up the length of impulse transmission

Pathway of Response
 Receptors detect a stimulus and produce an electric impulse as a result.
 This conveys information to sensory neurons (PNS) which carries impulses to the CNS.
 The relay neuron is the communicator neuron between the two, carrying information between sensory and
motor neurons.
 The CNS processes the impulses and sends information to the motor neurons (PNS), which sends impulses to
effectors.
 These effectors (muscles, glands, etc) produce a response.

Synapses
 Synapse: a junction between two individual neurons.
 Neurones communicate with each other across these junctions, using neurotransmitters
 An electrical impulse arrives at the pre-synaptic neuron. This arrival causes calcium ions to move into the
neuron, through calcium channels.
 The calcium ions cause vesicles in the neuron to move towards the pre-synaptic membrane. The vesicles
contain neurotransmitters.
 Once at the membrane, the vesicles fuse with it, releasing the neurotransmitters (NTs) inside them into the
synaptic cleft.
 The NTs diffuse across the cleft to the post-synaptic membrane – here, they attach to receptors on the post-
synaptic neuron.
 This triggers sodium channels to open in the post-synaptic neuron, causing sodium ions to enter the neuron.
This allows the electrical impulse to be initiated in the next neuron.
 We can also call nerve impulses action potentials.
 The junction from a neuron to a muscle fibre is called a neuromuscular junction (NMJ). This works in a very
similar way to a normal synapse – we just need to remember to call it a muscle cell, and not a post-synaptic
neuron!




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