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Sumario GUÍA DE ESTUDIO OSTEOPOROSIS - UNIVERSIDAD DE LA SABANA $8.49   Add to cart
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Sumario GUÍA DE ESTUDIO OSTEOPOROSIS - UNIVERSIDAD DE LA SABANA
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  • Course
  • Medicina interna
  • Institution
  • Universidad De La Sabana

Guía de estudio sencilla que cubre a profundidad los principales puntos de la osteoporosis, desde fisiopatología a manejo en los pacientes. Ideal para estudio.

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Document information

  • July 3, 2023
  • 3
  • 2022/2023
  • Summary

Subjects

  • osteoporosis
  • fractura
  • huesos
  • densitometría

Written for

  • Universidad De La Sabana
  • Medicina interna
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⑧SSFE8IPOROSS IIS
GENERALIDADES
· La osteoporosis es una enfermedad que se caracteriza por presencia de

disminución de densidad osea lo que aumenta riesgo de fracturas por



fragilidad
, una fractura por fragilidad se define como:



~
calda secundaria a un trauma de bajo impacto

~calda des de la propia altura o mas baja

·
1:2 museres
·
1:5 hombres

·
las fracturas más frequentes son vertebra, cadera y muneca

·
es enfermedad silente no presenta sintomas hasta la fractura
una que




FISIOPATOLOGIA
> METABOLISMO OSEO


1) WNT
coreceptores transmembrana
·
Ligando que se une a


osteoblasticos
y crea
genes
· Inhibido por DKK1 Y esclerostina



2) RANK -
RANKL -O4G

·
RANKL Se une al RANK Para promover la

resorción osea

· opo se une a KANKL Para inhiber la resorcion
o sea


↓ un disbalance en estos mecanismos nos lleva a la

osteoporosis




· Los principales FR van a ser


~envejecimiento

~menopausia=
La disminución de estrogenos lleva a *RANKL Y OPG
&




>Principales FR

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