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Edexcel A level Biology paper 1 2022 Questions
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Please check the examination details below before entering your candidate informationCandidate surname Other names
Centre Number Candidate Number
Pearson Edexcel
A Level
Paper
Time 1 hour 45 minutes
reference 9BI0/01
Biology
PAPER 1: 2022 Advanced
Biochemistry, Microbiology
and Genetics
You must have: Total Marks
Calculator, HB pencil, ruler
Instructions
• Use black ink or ball-point pen.
• centrethe
Fill in boxes at the top of this page with your name,
number and candidate number.
• Answer all questions.
• Show your working in any calculation questions and include units in your answer
where appropriate.
• Answer the questions in the spaces provided
– there may be more space than you need.
• You may use a scientific calculator.
• structure yourmarked
In questions with an asterisk (*), marks will be awarded for your ability to
answer logically showing how the points that you make are related or
follow on from each other where appropriate.
Information
• The total mark for this paper is 90.
• The marks for each question are shown in brackets
– use this as a guide as to how much time to spend on each question.
Advice
• Read each question carefully before you start to answer it.
• Checkanswer
Try to every question.
• Good luck
your answers if you have time at the end.
• with your examination. Turn over
*P65455A0132*
, Answer ALL questions.
Some questions must be answered with a cross in a box . If you change your mind about an
answer, put a line through the box and then mark your new answer with a cross .
1 The polymerase chain reaction (PCR) and gel electrophoresis are used to produce
DNA profiles.
The diagram shows DNA profiles, from an adult female, an adult male and each of
four children.
Adult Adult Child Child Child Child
female male 1 2 3 4
(a) Explain why PCR is used before gel electrophoresis to produce these DNA profiles.
(2)
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2
*P65455A0232*
, (b) Explain why gel electrophoresis produces individual DNA profiles.
(2)
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(c) Which of the children have both of these adults as their parents?
(1)
A child 1 and child 2
B child 1 and child 3
C child 2 and child 3
D child 2 and child 4
(Total for Question 1 = 5 marks)
3
Turn over *P65455A0332*
, 2 An investigation was carried out to compare the aerobic respiration of different sugars
by yeast.
A suspension of yeast was used to produce three cultures, each one with a different sugar.
A control was set up that had a suspension of yeast cultured with water only.
The volume of carbon dioxide produced was measured.
The mass of yeast and the concentration of each sugar were controlled.
The graph shows the results of this investigation.
25 maltose
20
15
Volume of
glucose
carbon dioxide
produced / cm3
10
5
water
lactose
0
0 10 20 30 40 50 60
Time / mins
(a) (i) Give one difference between the structure of glucose and the structure of maltose.
(1)
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4
*P65455A0432*
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