Summary
Summary Gene Expression and Central Dogma
- Course
- Institution
A summary on gene expression and central dogma.
[Show more]
Seller
Follow
thekrakenmid
Reviews received
Content preview
Gene Expression & Central DogmaGene Expression
Gene expression refers to the synthesis of a protein based on the DNA sequence of a
gene. The flow of information is from DNA to mRNA through transcription and then to
protein through translation. This concept is known as the central dogma of genetics.
Two Steps in Gene Expression
1. Transcription: A DNA sequence serves as a template for the synthesis of RNA
in the nucleus.
2. Translation: An mRNA sequence serves as a template for the synthesis of a
protein in the cytoplasm.
The Genetic Code
The genetic code is read three nucleotides at a time and specifies how genetic
information is converted from a nucleotide sequence to an amino acid sequence of a
protein. A set of three bases that determines the identity of one amino acid is called a
triplet. When a triplet is found in an mRNA molecule, it is called a codon.
Start and Stop Codons
The genetic code is always interpreted in terms of the mRNA codon, not the DNA
sequence. The start codon (AUG) signals to the ribosome that translation should begin,
while stop codons signal the end of translation to a ribosome.
Determining the Genetic Code To read the genetic code:
1. Find the first base column of the mRNA codon.
2. Read across the rows in the "second base" column to find the second letter of
the codon.
3. Read down the "third base" column to find the last letter of the codon.
4. The last letter, along with the previous two letters, identifies the amino acid
corresponding to the codon.
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller thekrakenmid. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $7.99. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
82191 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now