100% satisfaction guarantee Immediately available after payment Both online and in PDF No strings attached
logo-home
Uitgewerkte examenvragen immunologie UGent $6.59   Add to cart

Exam (elaborations)

Uitgewerkte examenvragen immunologie UGent

 35 views  0 purchase
  • Course
  • Institution

Uitgewerkte examenvragen immunologie 2e bachelor biochemie-biotechnologie UGent (Tussen haakjes staat bij elke vraag hoe vaak deze al gesteld werd op examens)

Preview 2 out of 13  pages

  • August 2, 2023
  • 13
  • 2023/2024
  • Exam (elaborations)
  • Questions & answers
avatar-seller
Functie mastcellen, eosinofielen en basofielen in immuunrespons
Eosinofielen
→ Vallen wormen aan
→ Drijven allergieën: ROS, toxines → weefselschade → nood aan regeneratie van
macrofagen

Granules bevatten:
- Neurotoxines
- Peroxidasen
- IL-4 → activatie mastcellen en basofielen

Basofielen
→ Vechten tegen wormen
→ Zorgen voor diarree → uitdrijving van wormen
Granules bevatten
- Histamine: dilatatie van aders (rekruteren cellen en serumcomponenten)
- Cytokines: IL4 en IL13 → Belang bij TH2 inductie (anti parasiet T-cell response)

Mastcellen
→ Vechten tegen wormen
→ Zorgen voor diarree → uitdrijving van wormen
→ Induceren allergieën: vrijstelling histamine & prostaglandine → induceren mucus
productie

Granules bevatten
- Histamines, IL4 & IL13 (minder dan basofiel)
- Prostaglandines (meer dan basofiel)

(3x) eosinofielen vergelijken met neutrofielen
Neutrofielen
Stellen volgende stoffen vrij:
- Cytokines: IL1, TNF → activatie andere immuuncellen
- ROS (toxisch voor bacteria)
- NETs om bacteria vast te houden (netosis)

Eosinofielen
→ Vallen wormen aan
→ Drijven allergieën: ROS, toxines → weefselschade → nood aan regeneratie van
macrofagen
Granules bevatten:
- Neurotoxines

1

, - Peroxidasen
- IL-4 → activatie mastcellen en basofielen

TLR7 en IL1 vergelijken
TLR7 dimeer → MyD88 → IRAK1-4 → IRF7 fosforylatie → Type I interferon (IFNα, IFN)
Typical for plasmacytoid DC (pDC) → anti-viral DC subset

IL-1R → MyD88 → IRAK1-4 → TRAF6 → TAK1 → IKK (α, β, γ) → I𝛋B degradation →
NF-𝛋B → TNF




TLR7 is more highly expressed on pDCs: better against viral infections

(4x) TLR-3 en TLR-5/TLR-4 met elkaar vergelijken: cel tekenen (om lokalisatie van de TLR’s
aan te tonen), de reactiepathway schetsen en uitleg geven bij de verschillende cytokines
die worden geproduceerd (volledig tekenen, liganden en afgeschreven genen geven)
TLR3 dimeer → TRIF → TRAF3 → IKKγ, IKKε, TBK1 → IRF3 fosforylatie → Type I interferon
(IFNα, IFNβ)
Typical for conventional DC (cDC1) → anti-viral DC subset

TLR5 dimeer → MyD88 → IRAK1-4 → TRAF6 → TAK1 → IKK (α, β, γ) → I𝛋B degradation
→ NF-𝛋B → TNF




2

The benefits of buying summaries with Stuvia:

Guaranteed quality through customer reviews

Guaranteed quality through customer reviews

Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.

Quick and easy check-out

Quick and easy check-out

You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.

Focus on what matters

Focus on what matters

Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!

Frequently asked questions

What do I get when I buy this document?

You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.

Satisfaction guarantee: how does it work?

Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.

Who am I buying these notes from?

Stuvia is a marketplace, so you are not buying this document from us, but from seller NVbiochem. Stuvia facilitates payment to the seller.

Will I be stuck with a subscription?

No, you only buy these notes for $6.59. You're not tied to anything after your purchase.

Can Stuvia be trusted?

4.6 stars on Google & Trustpilot (+1000 reviews)

57114 documents were sold in the last 30 days

Founded in 2010, the go-to place to buy study notes for 14 years now

Start selling
$6.59
  • (0)
  Add to cart