Necrosis - tissue death
Myocardial Infarction definition: - The development of ischemia with resultant necrosis of the myocardium caused from prolonged obstruction of the coronary arteries depriving the heart muscle of oxygen
Importance of oxygen in the body - reduces acidity
When do...
Myocardial Infarction definition: - The development of ischemia with resultant necrosis of the
myocardium caused from prolonged obstruction of the coronary arteries depriving the heart muscle of
oxygen
Importance of oxygen in the body - reduces acidity
When do most MI occur - between thanksgiving and new years because of all of the stress
Acute Myocardial infarction caused by - sudden thrombotic occulusion of a coronary artery
Acute Myocardial infarction occurs - at the site of an atherosclerotic plaque that has become unstable
due to a combination of ulceration, fissuring and rupture.
thrombosis - blood clot composed of platelets
Congestive heart failure occurs 25% of the time when - left ventricle is infarcted
ST-Segment Elevation is indicative of - MI
ST-Segment depression is indicative of - ischemia and angina
Most patients who sustain an MI have - coronary atherosclerosis.
A thrombus can become a - embolus
, Plaque rupture is believed to be the triggering mechanism for the development of a - thrombus
The thrombus formation occurs most often at the site of an - atherosclerotic lesion, thus obstructing
blood flow to the myocardial tissues.
80 - 90% of all MIs are derived from a - coronary thrombus
People with diabetes are more prone to - thrombus/embolus
What happens to a part of the body when ischemic? - inflammatory reaction, edema, platelet
aggregation, necrosis
Myocardium receives its blood supply from - 2 large coronary arteries and their branches
Most common site of MI - Left ventricle
Zone of infarction - region of ischemic damage
Ischemia and reperfusion injury is accompanied by an inflammatory response
Immediately surrounding the zone of infarction is a region called the - zone of hypoxic injury
What zone is reversible if blood perfusion is reestablished - Zone of Ischemia
MIs can be located in the - anterior, septal, lateral, posterior, or inferior walls of the left ventricle.
What factors determine the size of the resulting MI? - extent or severity of the ischemic episode, size of
vessel, amount of circulation, vascular tone, metabolic demands of the myocardium
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