5. Drug half-life is defined as the amount of time required for 50% of a drug to
a. be absorbed by the body.
b. reach a therapeutic level.
c. exert a response.
d. be removed by the body
6. The nurse recognizes that drugs given by which route will be altered by the first-pass
effect? (Select all that apply.)
a. Oral
b. Sublingual
c. Subcutaneous
d. Intravenous
e. Rectal
7. The nurse is reviewing a list of a patient’s medications and notes that one of the
drugs is known to have a low therapeutic index. Which statement accurately explains
this concept?
a. The difference between a therapeutic dose and toxic dose is large.
b. The difference between a therapeutic dose and toxic dose is small.
c. The dose needed to reach a therapeutic level is small.
d. The drug has only a slight chance of being effective.
8. The nurse prepares to obtain a patient’s blood sample from a central line for a drug
level that is to be drawn just before that medication’s next dose. What is the timing of
this blood draw known as?
a. Half-life
b. Therapeutic level
c. Peak level
d. Trough level
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